Radiprodil manufacturers
- Radiprodil
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- $41.00
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2026-05-11
- CAS:496054-87-6
- Purity: 99.90%
- Supply Ability: 10g
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| | Radiprodil Basic information |
| Product Name: | Radiprodil | | Synonyms: | Radiprodil;RGH 896;2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]-2-oxo-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide;RGH 896;RGH 896;RGH896;2-[4-(4-Fluorobenzyl)piperidin-1-yl]-2-oxo-N-(2-oxo-2,3-dihydrobenzoxazol-6-yl)acetamide;1-Piperidineacetamide, N-(2,3-dihydro-2-oxo-6-benzoxazolyl)-4-[(4-fluorophenyl)methyl]-α-oxo-;Radiprodil (RGH-896);Radiprodil,RGH896,Ionotropic glutamate receptors,RGH 896,iGluR,inhibit,Inhibitor | | CAS: | 496054-87-6 | | MF: | C21H20FN3O4 | | MW: | 397.41 | | EINECS: | | | Product Categories: | | | Mol File: | 496054-87-6.mol |  |
| | Radiprodil Chemical Properties |
| Melting point | 223-225 °C | | density | 1.394±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMF: 2mg/mL; DMSO: 10mg/mL; DMSO:PBS (pH 7.2) (1:3): 0.25mg/mL | | form | A solid | | pka | 8.62±0.70(Predicted) | | color | Light yellow to yellow |
| | Radiprodil Usage And Synthesis |
| Uses | Radiprodil is used in the preparation of oximides as novel NR2B selective NMDA receptor anatagonists. | | in vivo | Radiprodil could block NMDA currents in Mg2+ insensitive variants, with potencies similar to those obtained without Mg2+[3].
Radiprodil's potency is higher at pH 7.0 than at pH 7.6, suggesting that radiprodil may retain its ability to block glutamate-induced NMDA currents even under acidic conditions that manifest under long term seizures[3].
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| | Radiprodil Preparation Products And Raw materials |
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