N6-DiMethylaMinoMethylidene isoguanosine

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N6-DiMethylaMinoMethylidene isoguanosine Basic information
Product Name:N6-DiMethylaMinoMethylidene isoguanosine
Synonyms:N6-DiMethylaMinoMethylidene isoguanosine;N-[(Dimethylamino)methylene]-1,2-dihydro-2-oxoadenosine;Adenosine, N-[(dimethylamino)methylene]-1,2-dihydro-2-oxo- (9CI)
CAS:156706-72-8
MF:C13H18N6O5
MW:338.32
EINECS:
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Mol File:156706-72-8.mol
N6-DiMethylaMinoMethylidene isoguanosine Structure
N6-DiMethylaMinoMethylidene isoguanosine Chemical Properties
density 1.774±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka8.129±0.40(predicted)
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MSDS Information
N6-DiMethylaMinoMethylidene isoguanosine Usage And Synthesis
UsesN6-Dimethylaminomethylidene isoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
References[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
N6-DiMethylaMinoMethylidene isoguanosine Preparation Products And Raw materials
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