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2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine manufacturers
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| | 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine Basic information |
| Product Name: | 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine | | Synonyms: | 2'-Deoxy-2'-fluoro-arabinoisoguanosine;6-Amino-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-1,9-dihydro-2H-purin-2-one;2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine;2H-Purin-2-one, 6-amino-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-3,9-dihydro-;2'-Deoxy-2'-fluoro-2-hydroxy-b-D-arabinoadenosine;2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine,Clofara bine’s impurity B,DNA and RNA synthetase inhibitor;ClofarabineImpurity16;6-Amino-9-((2R,3S,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,9-dihydro-2H-purin-2-one | | CAS: | 899827-82-8 | | MF: | C10H12FN5O4 | | MW: | 285.23 | | EINECS: | | | Product Categories: | | | Mol File: | 899827-82-8.mol |  |
| | 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine Chemical Properties |
| | 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine Usage And Synthesis |
| Uses | 2-Hydroxy-2’-de oxy-2’-fluoro-beta-D-arabino adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. | | References | [1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005 |
| | 2-Hydroxy-2'-deoxy-2'-fluoro-beta-D-arabino adenosine Preparation Products And Raw materials |
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