N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide

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N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide manufacturers

  • FK962
  • FK962 pictures
  • $31.00
  • 2026-08-08
  • CAS:283167-06-6
  • Purity: 99.89%
  • Supply Ability: 10g
N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Basic information
Product Name:N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide
Synonyms:N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide;FK962;N-(1-acetylpiperidin-4-yl)-4-fluorobenzamide;Benzamide, N-(1-acetyl-4-piperidinyl)-4-fluoro-;Alzheimer,somatostatin,FK-962,FK 962,inhibit,FK962,Inhibitor,cognitive;FK962, 10 mM in DMSO;FK962 ，S0535
CAS:283167-06-6
MF:C14H17FN2O2
MW:264.3
EINECS:
Product Categories:
Mol File:283167-06-6.mol
N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Structure
N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Chemical Properties
storage temp. Sealed in dry,Room Temperature
solubility Soluble in DMSO
form Solid
color White to off-white
Safety Information
MSDS Information
N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Usage And Synthesis
UsesFK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions. Anti-dementia properties[1].
in vivo

FK962 (0.1, 0.3 or 1.0 mg/kg; i.p.) and Donepezil (a single dose of 1 mg/kg) act synergistically to improve cognition in rats: as an add-on therapy for Alzheimer's disease[2].

Animal Model:Male Lister Hooded rats, weighing approximately 270-300[2]
Dosage:0.1, 0.3 or 1.0 mg/kg; Donepezil was given as a single dose of 1 mg/kg
Administration:Administered i.p.
Result:Resulted in minimal cognition enhancement when given separately. Combination showed a significantly greater effect on cognition.
References[1] Tokita K, et al. FK962, a novel enhancer of somatostatin release, exerts cognitive-enhancing actions in rats. Eur J Pharmacol. 2005 Dec 19;527(1-3):111-20. DOI:10.1016/j.ejphar.2005.10.022
[2] McCarthy AD, et al. FK962 and donepezil act synergistically to improve cognition in rats: potential as an add-on therapy for Alzheimer's disease. Pharmacol Biochem Behav. 2011 Mar;98(1):76-80. DOI:10.1016/j.pbb.2010.11.019
N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide Preparation Products And Raw materials
Tag:N-(1-acetyl-4-piperidinyl)-4-fluoro-BenzaMide(283167-06-6) Related Product Information
N-Acetyllactosamine Cellulose acetate Sulfanilamide Methanone, [(3R)-3-amino-1-pyrrolidinyl](4-fluorophenyl)-, hydrochloride (1:1) Benzamide, 3-fluoro-N-(3-piperidinylmethyl)-, hydrochloride (1:1) N-(1-benzyl-4-piperidinyl)-4-fluorobenzamide