|
|
| | Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate Basic information |
| Product Name: | Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate | | Synonyms: | Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate;2,3-Dihydroxy-quinoxaline-6-carboxylic acid methyl ester;2,3-Dioxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid methyl ester;6-Quinoxalinecarboxylic acid, 1,2,3,4-tetrahydro-2,3-dioxo-, methyl ester | | CAS: | 354793-04-7 | | MF: | C10H8N2O4 | | MW: | 220.18 | | EINECS: | | | Product Categories: | | | Mol File: | 354793-04-7.mol |  |
| | Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate Chemical Properties |
| Melting point | >300℃ | | storage temp. | Sealed in dry,Room Temperature |
| | Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate Usage And Synthesis |
| Synthesis | The condensation reaction was carried out by reacting methyl 3,4-diaminobenzoate and diethyl oxalate (8.0 eq.) in toluene (10 v/v) under reflux conditions for 88 hours. After the reaction was complete, the reaction mixture was concentrated to dryness and the resulting residue was washed with methyl tert-butyl ether (MTBE). After drying, Intermediate 184 was obtained in 90% yield. | | References | [1] Patent: WO2017/60406, 2017, A1. Location in patent: Page/Page column 172
[2] Patent: WO2018/178280, 2018, A1. Location in patent: Page/Page column 78
[3] Patent: US2004/192698, 2004, A1. Location in patent: Page/Page column 18 |
| | Methyl 2,3-dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylate Preparation Products And Raw materials |
|