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| | ANTI-DMAP1 Basic information |
| Product Name: | ANTI-DMAP1 | | Synonyms: | Anti-DMAP1 (AB2) antibody produced in rabbit;Monoclonal Anti-DMAP1 antibody produced in mouse;Anti-DMAP1 (AB1) antibody produced in rabbit;Anti-DMAP1 (AB3) antibody produced in rabbit;ANTI-DMAP1;ANTI-DNA METHYLTRANSFERASE 1-ASSOCIATED PROTEIN 1;Anti-DNMAP1;Anti-DNMTAP1 | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![ANTI-DMAP1 Structure]() |
| | ANTI-DMAP1 Chemical Properties |
| storage temp. | -20°C | | form | buffered aqueous solution | | biological source | mouse |
| WGK Germany | nwg | | Storage Class | 10 - Combustible liquids |
| | ANTI-DMAP1 Usage And Synthesis |
| Uses | Rabbit Anti-DMAP1 antibody is suitable for western blot applications at a concentration of 5 μg/ml. | | General Description | This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. (provided by RefSeq) | | Biochem/physiol Actions | DMAP1 is a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described. |
| | ANTI-DMAP1 Preparation Products And Raw materials |
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