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| | 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE Basic information | | Synthesis |
| Product Name: | 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE | | Synonyms: | 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE;4-AMINO-2,3,5,6-TETRAFLUORROPYRIDINE;4-AMINOTETRAFLUOROPYRIDINE;2,3,5,6-Tetrafluoro-pyridin-4-ylamine;4-AMino-2,3,5,6-terafluoropyridine;4-Amino-2,3,5,6-tetrafluoropyridine 98%;4-Pyridinamine, 2,3,5,6-tetrafluoro-;2,3,5,6-tetrafluoro-4-pyridinamine | | CAS: | 1682-20-8 | | MF: | C5H2F4N2 | | MW: | 166.08 | | EINECS: | | | Product Categories: | Fluoropyridines;Halopyridines;C5;Heterocyclic Building Blocks;Pyridines;Pyridine;Heterocyclic Compounds;Building Blocks;Chemical Synthesis;Fluorinated Building Blocks;Heterocyclic Building Blocks;Heterocyclic Fluorinated Building Blocks;Other Fluorinated Heterocycles | | Mol File: | 1682-20-8.mol |  |
| | 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE Chemical Properties |
| Melting point | 85-87 °C (lit.) | | Boiling point | 85-86 °C | | density | 1.631±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | powder to crystal | | pka | -3.11±0.10(Predicted) | | color | White to Light yellow to Light orange | | BRN | 475870 | | InChI | InChI=1S/C5H2F4N2/c6-1-3(10)2(7)5(9)11-4(1)8/h(H2,10,11) | | InChIKey | PLVFNMQHMRRBAA-UHFFFAOYSA-N | | SMILES | C1(F)=NC(F)=C(F)C(N)=C1F | | CAS DataBase Reference | 1682-20-8(CAS DataBase Reference) |
| Hazard Codes | Xn,Xi | | Risk Statements | 20/21/22-36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Hazard Note | Irritant | | HS Code | 29333990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE Usage And Synthesis |
| Synthesis | In principle, ammonia could be used to allow indirect replacement of fluorine by
hydrogen. Workers in this laboratory showed that pentafluoropyridine reacted with
ammonia giving 4-aminotetrafluoropyridine.
 | | Chemical Properties | white to light yellow crystal | | Uses | 4-Amino-2,3,5,6-tetrafluoropyridine is formed as C-H ′insertion′ product during reaction with 4-azido-2,3,5,6-tetrafluoropyridine. | | General Description | 4-Amino-2,3,5,6-tetrafluoropyridine is formed as C-H ′insertion′ product during reaction with 4-azido-2,3,5,6-tetrafluoropyridine. | | References | [1] Journal of Fluorine Chemistry, 1996, vol. 81, # 1, p. 39 - 42
[2] Journal of the American Chemical Society, 2017, vol. 139, # 37, p. 13092 - 13101
[3] Oriental Journal of Chemistry, 2016, vol. 32, # 4, p. 1799 - 1813
[4] Journal of Organic Chemistry USSR (English Translation), 1988, vol. 24, # 12, p. 2267 - 2272
[5] Zhurnal Organicheskoi Khimii, 1988, vol. 24, # 12, p. 2513 - 2518 |
| | 4-AMINO-2,3,5,6-TETRAFLUOROPYRIDINE Preparation Products And Raw materials |
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