5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid

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5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid Basic information
Product Name:5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid
Synonyms:5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid;AMPK Activator;MPLLLQUZNJSVTK-UHFFFAOYSA-N;2-Furancarboxylic acid, 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]-;D942
CAS:849727-81-7
MF:C22H21FO4
MW:368.4
EINECS:
Product Categories:Activators, Aromatics
Mol File:849727-81-7.mol
5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid Structure
5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid Chemical Properties
storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml; DMSO: 25 mg/ml; Ethanol: 2 mg/ml
form A crystalline solid
color light yellow
InChI1S/C22H21FO4/c23-18-8-4-17(5-9-18)14-15-26-19-10-6-16(7-11-19)2-1-3-20-12-13-21(27-20)22(24)25/h4-13H,1-3,14-15H2,(H,24,25)
InChIKeyMPLLLQUZNJSVTK-UHFFFAOYSA-N
SMILESFc1ccc(cc1)CCOc2ccc(cc2)CCCc3[o]c(cc3)C(=O)O
Safety Information
WGK Germany WGK 1
Storage Class11 - Combustible Solids
MSDS Information
5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid Usage And Synthesis
Uses5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid, is an indirect activator of AMP-activated protein kinase, which is an enzyme that plays a role in cellular energy homeostasis.
Biological ActivityCell permeable: yes', 'EC50 = 11.7 μM enhancing glucose uptake in L6 myocytes', 'Primary Target
AMPK', 'Product does not compete with ATP.', 'Reversible: no
5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid Preparation Products And Raw materials
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