1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-

1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Suppliers list
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Products Intro: Product Name:N-Deacetyl Apremilast
CAS:253168-83-1
Purity:98% Package:100mg, 500mg, and 1gm
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Products Intro: Product Name:((S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (N- Deacetyl Apremilast)
CAS:253168-83-1
Purity:98% Package:1 kg,5 kg, 10 kg,25kg and 1 MT
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Products Intro: Product Name:1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-
CAS:253168-83-1
Purity:98%
Company Name: Shanghai Kewel Chemical Co., Ltd.  
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Products Intro: Product Name:Apremilast Impurity 100
CAS:253168-83-1
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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Products Intro: Product Name:1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-
CAS:253168-83-1
1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Basic information
Product Name:1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-
Synonyms:1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-;2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-aminoisoindoline-1,3-dione;1H-Isoindole-1,3(2H)-dione, 4-amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-;Apremilast Impurity 76;Apremilast Impurity 81;rac-Apremilast Impurity 11;4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione;((S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione (N- Deacetyl Apremilast)
CAS:253168-83-1
MF:C20H22N2O6S
MW:418.46
EINECS:
Product Categories:
Mol File:253168-83-1.mol
1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Structure
1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Chemical Properties
Boiling point 673.6±55.0 °C(Predicted)
density 1.383±0.06 g/cm3(Predicted)
pka-0.76±0.20(Predicted)
InChIInChI=1S/C20H22N2O6S/c1-4-28-17-10-12(8-9-16(17)27-2)15(11-29(3,25)26)22-19(23)13-6-5-7-14(21)18(13)20(22)24/h5-10,15H,4,11,21H2,1-3H3
InChIKeyBHJUWEUNUCJYER-UHFFFAOYSA-N
SMILESC1(=O)C2=C(C(N)=CC=C2)C(=O)N1C(C1=CC=C(OC)C(OCC)=C1)CS(C)(=O)=O
Safety Information
MSDS Information
1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Usage And Synthesis
Uses4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-1H-isoindole-1,3(2H)-dione is used in the apremilast acetylamino analogs preparation as oral PDE4 and TNF-α inhibitors.
1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]- Preparation Products And Raw materials
Tag:1H-Isoindole-1,3(2H)-dione, 2-[1-(3-ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethyl]-(253168-83-1) Related Product Information
Apremilast Impurity 84 N-[2-[1-(3-Ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]acetamide 3-Ethoxy-4-methoxy benzonitrile 3-Nitrophthalic acid Apremilast Impurity 19 Apremilast Impurity 15 Apremilast impurity 18 4-acetamidophthalic acid 1-Methyl-3-nitrophthalate 4-Nitrophthalic acid Apremilast Impurity 4 BenzeneMethanaMine, 4-ethoxy-3-Methoxy-a-[(Methylsulfonyl)Methyl]- Apremilast-d8 Apremilast Impurity 25 1-(3,4-Diethoxyphenyl)-2-(methylsulfonyl)ethan-1-amine Apremilast Impurity 28 (S)-1-(3-Ethoxy-4-Methoxyphenyl)-2-(Methylsulfonyl)ethylaMine N-acetyl-L-leucine salt Apremilast Impurity 34

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