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| | Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Basic information |
| Product Name: | Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate | | Synonyms: | 3-(N-ETHYL-M-TOLUIDINO)-2-HYDROXYPROPANE-SULFONIC ACID SODIUM SALT;3-(N-ETHYL-3-METHYLANILINO)-2-HYDROXYPROPANESULFONIC ACID SODIUM SALT;3-(n-ethyl-3-methylanilino)-2-hydroxypropansulf.acidso-salt;3-[ethyl(3-methylphenyl)amino]-2-hydroxy-1-propanesulfonicacimonosodiums;N-ETHYL-N-SULPHOHYDROXYPROPYL-M-TOLUIDINE, SODIUM SALT;N-ETHYL-N-SULFOHYDROXYPROPYL-M-TOLUIDINE SODIUM SALT;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-M-TOLUIDINE SODIUM SALT;N-ETHYL-N-(2-HYDROXY-3-SULFOPROPYL)-3-TOLUIDINE SODIUM SALT | | CAS: | 82692-93-1 | | MF: | C12H20NNaO4S | | MW: | 297.34 | | EINECS: | 617-377-8 | | Product Categories: | Pharmaceutical Raw Materials;detergent | | Mol File: | 82692-93-1.mol |  |
| | Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | form | Solid | | color | White to Almost white | | BRN | 5689521 | | InChI | InChI=1S/C12H19NO4S.Na.H/c1-3-13(8-12(14)9-18(15,16)17)11-6-4-5-10(2)7-11;;/h4-7,12,14H,3,8-9H2,1-2H3,(H,15,16,17);; | | InChIKey | IRQRBVOQGUPTLG-UHFFFAOYSA-M | | SMILES | N(C1C=CC=C(C)C=1)(CC)CC(O)CS(O)(=O)=O.[NaH] | | CAS DataBase Reference | 82692-93-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | F | 3 | | HS Code | 29214200 | | Storage Class | 11 - Combustible Solids |
| | Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Usage And Synthesis |
| Description | Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate is a water-soluble reagent used in the enzymatic photometric determination of hydrogen peroxide. This compound is a widely studied small molecule inhibitor in scientific research. Originally synthesized in the early 1980s, it has since found extensive use in various investigations into cellular processes. It has its inhibition of the Na+/H+ exchanger (NHE), which is a membrane protein crucial for regulating intracellular pH. Additionally, EIPA has shown its potential as an inhibitor of TRPV channels, which play a role in pain sensation and thermoregulation. Another significant finding indicates Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate′s inhibition of the Na+/Ca2+ exchanger (NCX), responsible for regulating intracellular calcium levels.
| | Chemical Properties | White crystalline powder | | Uses | TOOS (TOOS sodium salt) is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. TOOS can be combined with 3-methyl-2-benzothiazolinone hydrazone hydrochloride (MBTH) to form a chromogenic system to measure oxidase activity. In the MBTH-TOOS chromogenic system, MBTH is catalytically oxidized to produce (-NH) free radicals, which react with TOOS to form colorless compounds. Furthermore, the colorless compound undergoes a disproportionation reaction to produce a blue-violet quinoid compound[1]. | | References | [1] Lin X, et al. Boosting the oxidase-like activity of platinum nanozyme in MBTH-TOOS chromogenic system for detection of trypsin and its inhibitor. Talanta. 2021 Nov 1;234:122647. DOI:10.1016/j.talanta.2021.122647 |
| | Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate Preparation Products And Raw materials |
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