- Fmoc-Gly-OH
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- $0.00 / 1kg
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2026-01-23
- CAS:29022-11-5
- Min. Order: 1kg
- Purity: 98+
- Supply Ability: 1T
- FMOC-Glycine
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- $0.00 / 25kg
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2026-01-23
- CAS:29022-11-5
- Min. Order: 1kg
- Purity: 98%min
- Supply Ability: 1000kg
- Fmoc-Gly-OH
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- $2.00 / 1KG
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2025-09-25
- CAS:29022-11-5
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: g-kg-tons, free sample is available
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| | Fmoc-Gly-OH Basic information |
| | Fmoc-Gly-OH Chemical Properties |
| Melting point | 174-175 °C(lit.) | | Boiling point | 438.82°C (rough estimate) | | density | 1.1671 (rough estimate) | | refractive index | 1.4500 (estimate) | | storage temp. | 2-8°C | | solubility | almost transparency in Methanol | | pka | 3.89±0.10(Predicted) | | form | Powder | | color | White | | BRN | 2163967 | | Major Application | peptide synthesis | | InChI | InChI=1S/C17H15NO4/c19-16(20)9-18-17(21)22-10-15-13-7-3-1-5-11(13)12-6-2-4-8-14(12)15/h1-8,15H,9-10H2,(H,18,21)(H,19,20) | | InChIKey | NDKDFTQNXLHCGO-UHFFFAOYSA-N | | SMILES | C(O)(=O)CNC(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)=O | | CAS DataBase Reference | 29022-11-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 24/25-36-26 | | WGK Germany | 3 | | HS Code | 29242995 | | Storage Class | 11 - Combustible Solids |
| | Fmoc-Gly-OH Usage And Synthesis |
| Chemical Properties | white to light yellow crystal powde | | Uses | Fmoc-Gly-OH is an N-Fmoc-protected form of Glycine (G615990). Glycine is a nonessential amino acid that acts as an inhibitory neyrotransmitter in the vertebrate central nervous system. Glycine also posesses cytoprotective against oxidant damage in the kidney. | | Preparation | Glycine (Gly) (0.5 g, 6.66 mmol) was dissolved in 10% NaCO3 (14 ml) under stirring in a 50-ml flask. To the resulting solution, which had been put into an ice bath, 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl) (1.72 g, 6.66 mmol) in dioxane (12 ml) was gradually added. The reaction mixture was stirred at room temperature for 4 hours. Then added water (150 ml) to the mixture. The aqueous phase layer was separated from the reaction mixture and stripped with ether three times (75 ml×3). The stripped aqueous layer was acidified with 2N HCl aqueous solution to a pH=2, followed by extraction with ethyl acetate three times (75 ml×3). The organic phase layer was recovered and concentrated to obtain crude product of 1.70 g. The crude product was recrystallized in a mixed solvent of ethyl acetate hexane=1:2 (30 ml), and white solid denoted as Fmoc-Gly-OH was obtained after filtration at a reduced pressure.
 | | General Description |
Fmoc-Gly-OH is used for fmoc solid-phase peptide synthesis.
| | reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| | Fmoc-Gly-OH Preparation Products And Raw materials |
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