Methyl 2-oxoacetate

Methyl 2-oxoacetate Suppliers list
Company Name: Baiyin letianyuan chemical co., LTD  Gold
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Company Name: Chemsky (shanghai) International Co.,Ltd  
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Company Name: Hangzhou Sage Chemical Co., Ltd.  
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Methyl 2-oxoacetate manufacturers

  • Methyl 2-oxoacetate
  • Methyl 2-oxoacetate pictures
  • $9.80
  • 2019-12-26
  • CAS:922-68-9
  • Min. Order: 1g
  • Purity: ≥99%
  • Supply Ability: 100kg
Methyl 2-oxoacetate Basic information
Product Name:Methyl 2-oxoacetate
Synonyms:2-(2-METHOXYPHENOXY)ETHANAMINE HCL;2-(2-METHOXYPHENOXY)ETHYLAMINE HCL;2-(2-METHOXPHENOXYL)ETHYLAMINE MONOHYDROCHLORIDE;2-(2-METHOXPHENOXYL) ETHYLAMINE HCL;2-(METHOXY PHENOXY)ETHYLAMINE HYDROCHLORIDE;GLYOXYLIC ACID METHYL ESTER;Methyl oxoacetate;oxo-aceticacimethylester
CAS:922-68-9
MF:C3H4O3
MW:88.06
EINECS:213-084-0
Product Categories:Miscellaneous Reagents
Mol File:922-68-9.mol
Methyl 2-oxoacetate Structure
Methyl 2-oxoacetate Chemical Properties
Melting point 40-42°C
Boiling point 102.98°C (rough estimate)
density 1.2076 (rough estimate)
refractive index 1.3720 (estimate)
solubility sol H2O; sol most organic solvents, e.g. ether, CH2Cl2, THF, acetone, etc.
InChIInChI=1S/C3H4O3/c1-6-3(5)2-4/h2H,1H3
InChIKeyKFKXSMSQHIOMSO-UHFFFAOYSA-N
SMILESC(OC)(=O)C=O
CAS DataBase Reference922-68-9(CAS DataBase Reference)
NIST Chemistry ReferenceMethyl glyoxylate(922-68-9)
EPA Substance Registry SystemAcetic acid, oxo-, methyl ester (922-68-9)
Safety Information
Risk Statements 36/37/38
Safety Statements 26-36/37/39
TSCA TSCA listed
MSDS Information
Methyl 2-oxoacetate Usage And Synthesis
UsesMethyl Glyoxylate is a useful compound for preparation of pyridine and quinoline derivatives.
PreparationPreparative Methods of Methyl 2-oxoacetate: efficient methods include oxidative cleavage of tartrate diesters, ozonolysis of maleate/fumarate derivatives, exchange reaction between appropriate dialkoxyacetate and glyoxylic acid, and NaOAc-catalyzed elimination of nitrite ion from nitrate esters.[1]
General DescriptionMethyl Glyoxylate is a two-carbon synthon utilized in electrocyclic processes (Diels-Alder reaction, ene reactions), various condensations (Mannich, aldol, Wittig, Prins, acyloin), carbinolamine formation, and Friedel-Crafts reactions.
storageMethyl 2-oxoacetate stores under N2 in a refrigerator due to their tendency to form a monohydrate and/or polymerize.
References1. (a) Wolf, F. J.; Weijland, J. OSC 1963, 4, 124. (b) Jung, M. E.; Shishido, K.; Davis, L. H. JOC 1982, 47, 891. (c) Blake, J.; Tretter, J. R.; Juhasz, G. J.; Bonthrone, W.; Rappoport, H. JACS 1966, 88, 4061. (d) Haggerty, J. G.; Kelly, T. R.; Schmidt, T. E. S 1972, 544. Hook, J. M. SC 1984, 14, 83. (e) Kornblum, N.; Frazier, H. W. JACS 1966, 88, 865.
Methyl 2-oxoacetate Preparation Products And Raw materials
Preparation ProductsMETHYL-2-CHLOROOXAZOLE-5-CARBOXYLATE-->methyl (2Z)-2-hydroxyiminoacetate-->2-(2-Oxocyclohexyl)-2-hydroxy-acetic acid methyl ester
Tag:Methyl 2-oxoacetate(922-68-9) Related Product Information
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