| Company Name: |
Accela ChemBio Co.,Ltd.
|
| Tel: |
021-50795510 4000665055 |
| Email: |
marketing@accelachem.com |
| Products Intro: |
Product Name:5-Chloro-2-iodoindole
CAS:1388032-50-5
Purity:>95% Package:0.1g;0.25g;1g;5g;10g
|
| Company Name: |
Aikon International Limited
|
| Tel: |
025-66061636 19370895928 |
| Email: |
qqyang@aikonchem.com |
| Products Intro: |
Product Name:5-Chloro-2-iodo-1H-indole
CAS:1388032-50-5
Purity:95+% Package:1g;5g;10g
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Email: |
marketing1@energy-chemical.com |
| Products Intro: |
Product Name:5-Chloro-2-iodo-1H-indole
CAS:1388032-50-5
Purity:97% Package:1g;250mg;5g;0.25g;1g;5g;1g Remarks:NULL
|
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| | 5-Chloro-2-iodoindole Basic information |
| | 5-Chloro-2-iodoindole Chemical Properties |
| Boiling point | 375.6±22.0 °C(Predicted) | | density | 2.041±0.06 g/cm3(Predicted) | | storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C | | pka | 14.65±0.30(Predicted) |
| | 5-Chloro-2-iodoindole Usage And Synthesis |
| Synthesis | GENERAL METHOD: To a stirred solution of compound 7 (1 mmol) in tetrahydrofuran (THF, 20 mL) was added tetrabutylammonium fluoride (TBAF, 1 mL, 1 M solution of THF, 1 mmol) at room temperature. The reaction mixture was stirred continuously at ambient temperature for 5 hours. After completion of the reaction, the mixture was partitioned between ethyl acetate (EtOAc, 100 mL) and water (H2O, 50 mL). The organic phase was separated and washed with brine (50 mL) and subsequently dried over anhydrous sodium sulfate (Na2SO4). The dried organic phase was concentrated and purified by automated fast chromatography using ethyl acetate (EtOAc) and hexane as eluents to give the final compound 8. | | References | [1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 5, p. 1708 - 1725 |
| | 5-Chloro-2-iodoindole Preparation Products And Raw materials |
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