- BrCH2CONH-PEG3-NHBoc
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2025-06-07
- CAS:1421933-39-2
- Min. Order: 10g
- Purity: >98.00%
- Supply Ability: 10g
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| | Bromoacetamido-PEG3 -Boc-amine Basic information |
| Product Name: | Bromoacetamido-PEG3 -Boc-amine | | Synonyms: | Bromoacetamido-PEG3 -Boc-amine;Bromoacetamido-PEG3-NH-Boc;5,8,11-Trioxa-2,14-diazahexadecanoic acid, 16-bromo-15-oxo-, 1,1-dimethylethyl ester;Bromoacetamido-PEG4-t-Boc-N-Amide;tert-Butyl (1-bromo-2-oxo-6,9,12-trioxa-3-azatetradecan-14-yl)carbamate;BrCH2CONH-PEG3-NHBoc;N-[2-[2-[2-[2-(Boc-amino)ethoxy]ethoxy]ethoxy]ethyl]-2-bromoacetamide | | CAS: | 1421933-39-2 | | MF: | C15H29BrN2O6 | | MW: | 413.3 | | EINECS: | | | Product Categories: | | | Mol File: | 1421933-39-2.mol |  |
| | Bromoacetamido-PEG3 -Boc-amine Chemical Properties |
| storage temp. | Storage temp. 2-8°C | | solubility | DMF: 10mg/mL,Ethanol: 10mg/mL | | form | A liquid | | color | Light yellow to yellow |
| | Bromoacetamido-PEG3 -Boc-amine Usage And Synthesis |
| Description | Bromoacetamido-PEG3-Boc-amine is a PEG linker containing a Boc protected amine and a bromide group. The protected amine can be deprotected under mild acidic conditions. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | Bromoacetamido-PEG3-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Bromoacetamido-PEG3 -Boc-amine Preparation Products And Raw materials |
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