| Company Name: |
Changzhou Hopschain Chemical Co.,Ltd.
|
| Tel: |
85528066 13775048983 |
| Email: |
sales@hopschem.com |
| Products Intro: |
Product Name:2-fluoro-5-methyl-4-nitrophenol
CAS:63762-80-1
Purity:95+% Package:100mg;250mg;500mg;1g;2.5g;5g;10g
|
| Company Name: |
BePharm Ltd
|
| Tel: |
400-685-9117 |
| Email: |
market@bepharm.com |
| Products Intro: |
Product Name:2-Fluoro-5-methyl-4-nitrophenol
CAS:63762-80-1
Purity:98% Package:3672RMB/1g
|
| Company Name: |
SuZhou Medinoah Co.,LTD.
|
| Tel: |
0512-69561983 13914027025 |
| Email: |
zhang_q@medinoah.com |
| Products Intro: |
Product Name:2-Fluoro-5-methyl-4-nitrophenol
CAS:63762-80-1
Purity:>95% Package:5g;10g;1kg;10kg;>10kg 大货
|
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| | 2-Fluoro-5-methyl-4-nitrophenol Basic information | | Synthesis |
| | 2-Fluoro-5-methyl-4-nitrophenol Chemical Properties |
| Boiling point | 288.5±40.0 °C(Predicted) | | density | 1.423±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | pka | 5.94±0.24(Predicted) | | Appearance | Light yellow to yellow Solid |
| | 2-Fluoro-5-methyl-4-nitrophenol Usage And Synthesis |
| Synthesis | Added 2-fluoro-5-methylphenol (0.200 g, 1.59 mmol) to a
5 mL flask followed by AcOH (0.40 mL) and H2SO4 (0.058 mL) at 0 ⁰C (ice-salt bath). Then
sodium nitrite (0.29 mL of 5.5 M in water) was slowly added to the reaction to give a burnt
orange color. The reaction was stirred for 30 min on the ice bath. Poured reaction over ice and
then filtered off a light orange solid. Warmed 20% nitric Acid in water (5 mL) to 45 ⁰C then
added the orange solid in portions while stirring. The reaction was stirred for twenty min then
diluted with water and cooled. The light orange solid was filtered off to give 2-fluoro-5-methyl-
4-nitrophenol as a light orange solid (0.124g, 46% yield). 1H NMR (500 MHz, DMSO-d6) δ
13.86 (s, 1H), 7.42 (d, J = 11.6 Hz, 1H), 6.47 (dq, J = 8.2, 1.3 Hz, 1H), 2.23 (d, J = 1.3 Hz, 3H). |
| | 2-Fluoro-5-methyl-4-nitrophenol Preparation Products And Raw materials |
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