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| | N-(m-PEG4)-N'-hydroxypropyl-Cy5 Basic information |
| | N-(m-PEG4)-N'-hydroxypropyl-Cy5 Chemical Properties |
| solubility | Soluble in Water, DMSO, DMF, DCM |
| | N-(m-PEG4)-N'-hydroxypropyl-Cy5 Usage And Synthesis |
| Description | N-(m-PEG4)-N'-hydroxypropyl-Cy5 is a cyanine labeled PEG linker with excitation/emmission maximum 649/667 nm containing hydroxyl group, which enables further derivatized or replaced with other reactive functional groups. Hydophilic PEG spacer increases solubility in aqueous media and reduces steric hindrance during binding. | | Uses | N-(m-PEG4)-N'-hydroxypropyl-Cy5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | N-(m-PEG4)-N'-hydroxypropyl-Cy5 Preparation Products And Raw materials |
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