4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Suppliers list

Company Name:	Puyang Huicheng Electronic Materials Co., Ltd.
Tel:	+86-0393-+86-0393-8910800 +8615839383373
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Products Intro:	Product Name:4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS:1770840-43-1 Purity:98% Package:1000g;0USD

Company Name:	Baoji Guokang Healthchem co.,ltd
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Email:	dominicguo@gk-bio.com
Products Intro:	Product Name:4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS:1770840-43-1 Purity:0.99 Package:5KG;1KG.100g

Company Name:	Affinity（Wuhan）Ltd.
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Products Intro:	Product Name:7-iodopyrrolo[2,1-f][1,2,4]triazin-4-amine CAS:1770840-43-1 Purity:98% Package:1kg

Company Name:	Hebei Chuanghai Biotechnology Co., Ltd
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Products Intro:	Product Name:4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS:1770840-43-1 Purity:99% Package:1KG;30.00;USD\|10KG;20.00;USD\|100KG;10.00;USD

Company Name:	HANGZHOU LEAP CHEM CO., LTD.
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Products Intro:	Product Name:4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine CAS:1770840-43-1 Purity:0 Package:1g; 5g; 25g; 1kg; 5kg; 25kg Remarks:0

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine manufacturers

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Basic information

Product Name:	4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine
Synonyms:	4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine;Starting material);Remdesivir-004;4-Amino-7-iodopyrroL;o[2,1-f][1,2,4]triazine;7-iodopyrrole[2,1-f][1,2,4]triazin-4-amine;Remdesivir Impurity 20;Pyrrolo[2,1-f][1,2,4]triazin-4-amine, 7-iodo-
CAS:	1770840-43-1
MF:	C6H5IN4
MW:	260.04
EINECS:	204-514-8
Product Categories:	J's;3;1770840-43-1
Mol File:	1770840-43-1.mol

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Chemical Properties

density	2.43±0.1 g/cm3(Predicted)
form	solid
pka	3.04±0.30(Predicted)
color	Pale yellow
InChI	InChI=1S/C6H5IN4/c7-5-2-1-4-6(8)9-3-10-11(4)5/h1-3H,(H2,8,9,10)
InChIKey	ZEBGLCLVPCOXIV-UHFFFAOYSA-N
SMILES	N12C(I)=CC=C1C(N)=NC=N2

Safety Information

HS Code

2933998090

MSDS Information

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Usage And Synthesis

Uses	4-amino-7-iodopyrrolo[2,1-f][1,2,4]triazine is an amine organic substance and can be used as an intermediate for APIs.
Uses	7-Iodopyrrolo[2,1-f][1,2,4]triazin-4-amine is a useful reagent in the synthesis of phosphoramidate GS-5734 prodrug for potential treatment of Ebola virus infections and in the preparation of Remdesivir as COVID-19 antiviral drug candidate.
Synthesis	The synthesis reaction of 4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine is as follows: 4-amino pyrrolo [2,1-f ] [1,2,4] triazine reacts with iodine or iodine chloride under mild conditions to generate most of iodinated products, isomers and diiodized products are not generated under the mild conditions, and unreacted materials react with N-iodosuccinimide to further ensure that raw materials completely react, so that the conversion rate of the raw materials is improved, and the generation of the isomer products and the diiodized products is also inhibited.

4-amino-7-iodopyrrolo [2,1-f ] [1,2,4] triazine Preparation Products And Raw materials

Preparation Products

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