Apelin-12 (human, bovine, mouse, rat)
| 中文名称 | Apelin-12 (human, bovine, mouse, rat) |
|---|---|
| 中文同义词 | RF-12;小鼠APELIN-12ELISA试剂盒;爱帕琳肽-12;爱帕琳肽(阿佩林肽)APELIN-12 (HUMAN, BOVINE, MOUSE, RAT);人、牛、小鼠、大鼠Apelin-12;人apelin 12ELISA试剂盒 |
| 英文名称 | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH |
| 英文同义词 | (Des-Gln1)-Apelin-13 (huMan, bovine, Mouse, rat), Apelin Precursor (66-77) (huMan, bovine, Mouse, rat), Preproapelin (66-77) (huMan, bovine, Mouse, rat);Apelin-12,(Des-Gln1)-Apelin-13;Apelin-12 (human, bovine, mouse, rat) H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH;Apelin-12 (huMan, bovine, Mouse, rat) (Des-Gln1)-Apelin-13 (huMan, bovine, Mouse, rat), Apelin Precursor (66-77) (huMan, bovine, Mouse, rat), Preproapelin (66-77) (huMan, bovine, Mouse, rat);H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH;(DES-GLN1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT);APELIN PRECURSOR (66-77) (HUMAN, BOVINE, MOUSE, RAT);APELIN 12 |
| CAS号 | 229961-08-4 |
| 分子式 | C64H103N21O14S |
| 分子量 | 1422.7 |
| EINECS号 | |
| 相关类别 | 多肽;目录多肽;Apelin receptor;peptide |
| Mol文件 | 229961-08-4.mol |
| 结构式 |  |
Apelin-12 (human, bovine, mouse, rat) 性质
| RTECS号 | CD7310000 |
|---|---|
| 储存条件 | -15°C |
| 形态 | 冻干粉 |
| 颜色 | 白色至米白色 |
| 序列 | H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH |
| InChIKey | KIODTAJAFBDDGP-TZIGXLGFSA-N |
Apelin-12 是多肽中最有效的 C 端片段之一，对孤儿受体 APJ 受体具有很高的亲和力。Apelin-12 参与体液平衡的调节和摄食的中枢控制。Apelin-12 阻断HIV-1通过 APJ 受体进入。Apelin-12 具有神经保护作用。
纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
Apelin-12 (A12) exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and p38 MAPK signaling pathway in mouse.
Administration of exogenous A12 reduces arterial blood pressure in anesthetized rats due to activation of endothelial nitric oxide synthase and exerts a positive inotropic action in failing myocardium of rodents.
Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs.
多肽
Apelin-12 (human, bovine, mouse, rat)由12个氨基酸组成，广泛存在于哺乳动物体内，其主要生理作用是调节由血小板聚集障碍所引起的出血，还可以调节血小板聚集水平以及防止血栓形成。参考质量标准
外观:白色粉末纯度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
内毒素≤50EU/mg
氨基酸组成分析≤±10%
安全信息
| 更新日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
|---|---|---|---|---|---|
| 2026/06/05 | HY-P2537 | Apelin-12 | 229961-08-4 | 1 mg | 1590元 |
| 2026/06/05 | HY-P2537 | ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE Apelin-12 | 229961-08-4 | 5mg | 3500元 |