(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid

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(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid manufacturers

  • S 3304
  • S 3304 pictures
  • $68.00
  • 2026-08-08
  • CAS:203640-27-1
  • Purity: 98.09%
  • Supply Ability: 10g
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Basic information
Product Name:(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid
Synonyms:(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid;R-3-(1H-Indol-3-yl)-2-(5-(p-tolyleth ynyl)thiophene-2;(2R)-3-(1H-indol-3-yl)-2-{5-[2-(4-methylphenyl)ethynyl]thiophene-2-sulfonamido}propanoic acid;(2R)-3-(1H-indol-3-yl)-2-[[5-[2-(4-methylphenyl)ethynyl]thiophen-2-yl]sulfonylamino]propanoic acid;D-Tryptophan, N-[[5-[2-(4-methylphenyl)ethynyl]-2-thienyl]sulfonyl]-;(R)-3-(1H-Indol-3-yl)-2-(5-p-tolylethynyl-thiophene-2-sulfonylamino)-propionic acid;S 3304,Inhibitor,inhibit,S3304,MMP,S-3304,Matrix metalloproteinases;S 3304, 10 mM in DMSO
CAS:203640-27-1
MF:C24H20N2O4S2
MW:464.56
EINECS:
Product Categories:
Mol File:203640-27-1.mol
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Structure
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Chemical Properties
Boiling point 745.7±70.0 °C(Predicted)
density 1.47±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Aqueous Base (Slightly), DMSO (Slightly)
form Solid
pka3.29±0.10(Predicted)
color Pale Beige to Light Beige
Safety Information
MSDS Information
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Usage And Synthesis
DescriptionS-3304 is a sulfonamide derivative that acts as a matrix metalloproteinase inhibitor.
UsesS 3304, is a novel matrix metalloproteinases (MMP) inhibitor specific for MMP-2 and MMP-9.
in vivo

In vivo pharmacologic studies have shown that the oral administration of S 3304, at a dose range of 20 to 200 mg/kg, inhibits angiogenesis, artificially induced in mice by the dorsal air-sac method. Similar oral doses of S 3304 result in potent inhibition of metastatic lung colonization of Lewis murine lung carcinoma injected via tail vein and liver metastasis of C-1H human colon cancer implanted into the spleen[1].

IC 50MMP-9
(R)-3-(1H-Indol-3-yl)-2-(5-(p-tolylethynyl)thiophene-2-sulfonamido)propanoic acid Preparation Products And Raw materials
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