N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide

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N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide manufacturers

  • AST 7062601
  • AST 7062601 pictures
  • $70.00
  • 2026-08-08
  • CAS:675197-89-4
  • Purity: 99.34%
  • Supply Ability: 10g
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide Basic information
Product Name:N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide
Synonyms:N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide;AST 7062601;AST070;N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((4-oxo-3,4-dihydroquinazolin-2-yl)thio)acetamide
CAS:675197-89-4
MF:C18H15N3O4S
MW:369.3944
EINECS:
Product Categories:
Mol File:675197-89-4.mol
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide Structure
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide Chemical Properties
Safety Information
MSDS Information
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide Usage And Synthesis
UsesAST 7062601 (AST070) is a Ucp1 inducer that strongly induces endogenous Ucp1 expression in primary mouse brown adipocytes. Ucp1 refers to uncoupling protein, found in brown and beige fat cells. In mammals, UCP1 oxidizes fatty acids and uncouples ATP production in mitochondria to promote energy dissipation as heat. AST 7062601 can be used to study thermogenic, uncoupled respiration[1].
References[1] Vergnes L, et al. Induction of UCP1 and thermogenesis by a small molecule via AKAP1/PKA modulation. J Biol Chem. 2020 Oct 30;295(44):15054-15069. DOI:10.1074/jbc.RA120.013322
N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide Preparation Products And Raw materials
Tag:N-(2,3-dihydro-1,4-benzodioxin-6-yl)-2-[(4-oxo-1H-quinazolin-2-yl)sulfanyl]acetamide(675197-89-4) Related Product Information
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