Rafoxanide

Rafoxanide Suppliers list

Company Name:	Hebei Chuanghai Biotechnology Co., Ltd
Tel:	+8615350571055
Email:	Sibel@chuanghaibio.com
Products Intro:	Product Name:Rafoxanide CAS:22662-39-1 Purity:99% Package:1KG;10.00;USD

Company Name:	Shaanxi TNJONE Pharmaceutical Co., Ltd
Tel:	+8618092446649
Email:	sarah@tnjone.com
Products Intro:	Product Name:Rafoxanide CAS:22662-39-1 Purity:99% Package:1kg

Company Name:	Henan Tianfu Chemical Co.,Ltd.
Tel:	+86-0371-55170693 +86-19937530512
Email:	info@tianfuchem.com
Products Intro:	Product Name:TIANFU-CHEM CAS:22662-39-1 Rafoxanide CAS:22662-39-1 Purity:99% Package:25KG;5KG;1KG

Company Name:	career henan chemical co
Tel:	+86-0371-86658258 +8613203830695
Email:	sales@coreychem.com
Products Intro:	Product Name:Rafoxanide CAS:22662-39-1 Purity:99% Package:1kg;7USD

Rafoxanide manufacturers

Rafoxanide Basic information

Product Name:	Rafoxanide
Synonyms:	3’-chloro-4’-(p-chlorophenoxy)-3,5-diiodo-salicylanilid;3’-chloro-4’-(p-chlorophenoxy)-3,5-diiodosalicylanilide;bovanide;duofas;flukanide;Rafoxanide 0.1;N-[3-chloro-4-(4-chlorophenoxy)phenyl]-3,5-diiodobenzamide;Disalan
CAS:	22662-39-1
MF:	C19H11Cl2I2NO3
MW:	626.01
EINECS:	245-148-9
Product Categories:	Used to kill trematode medicine;API;Rafoxanide;22662-39-1
Mol File:	22662-39-1.mol

Rafoxanide Chemical Properties

Melting point	168-170°
Boiling point	526.6±50.0 °C(Predicted)
density	2.050±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly)
pka	6.04±0.48(Predicted)
form	Solid
color	White to Off-White
Merck	14,8097
Major Application	agriculture environmental
InChI	InChI=1S/C19H11Cl2I2NO3/c20-10-1-4-13(5-2-10)27-17-6-3-12(9-15(17)21)24-19(26)14-7-11(22)8-16(23)18(14)25/h1-9,25H,(H,24,26)
InChIKey	NEMNPWINWMHUMR-UHFFFAOYSA-N
SMILES	C(NC1=CC=C(OC2=CC=C(Cl)C=C2)C(Cl)=C1)(=O)C1=CC(I)=CC(I)=C1O
CAS DataBase Reference	22662-39-1(CAS DataBase Reference)

Safety Information

MSDS Information

Rafoxanide Usage And Synthesis

Chemical Properties

White to Off-White Solid

Uses

Rafoxanide is a thyroid hormone receptor.

in vivo

Rafoxanide (7.5 mg/kg, i.p., once every 2 d for 88d) reduces colonic tumorgenesis in Apc^min/+ mice^[3].

Animal Model:	AOM induced Apc^min/+ mice^[3]
Dosage:	7.5 mg/kg
Administration:	Intraperitoneal injection (i.p.), once every 2 d for 88d
Result:	Exerted less number and size of AOM induced lesions in the colon. No significant body weight changes were observed. Detected adenomas (28.6%), advanced adenomas (67.8%) and adenocarcinoma (3.6%) in control group as adenomas (33.3%), advanced adenomas (25%%) and no obvious lesions(41.6%) were detected in treated group. Caused increased signal for p-eIF2α, CHOP and cleaved caspase-3 in tumor tissues while these signal in non-tumor colon epithelium were barely detectable.

IC 50

Schistosome

Rafoxanide Preparation Products And Raw materials

Raw materials

Tag:Rafoxanide(22662-39-1) Related Product Information

Salicylaldehyde p-Anisidine o-Anisidine Amiodarone m-Anisidine Amiodarone hydrochloride Iopromide 4-(Trifluoromethoxy)aniline Sodium 4-aminosalicylate dihydrate Fatty amine polyoxyethylene ether Sodium salicylate FLUPOXAM 3-CHLORO-4-HYDROXYACETANILIDE 2-HYDROXY-5-IODO-BENZALDEHYDE 3,5-DIIODOSALICYLALDEHYDE Difluorochloromethane 3-Iodobenzylamine hydrochloride 3-IODOBENZAMIDE

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