(Z)-3-oxo-N-[(3S)-2-oxooxolan-3-yl]hexadec-11-enamide manufacturers
- 3-Oxo-C16:1
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- $108.00
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2026-07-17
- CAS:1269663-80-0
- Purity:
- Supply Ability: 10g
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| | (Z)-3-oxo-N-[(3S)-2-oxooxolan-3-yl]hexadec-11-enamide Basic information |
| | (Z)-3-oxo-N-[(3S)-2-oxooxolan-3-yl]hexadec-11-enamide Chemical Properties |
| Boiling point | 584.4±50.0 °C(Predicted) | | density | 1.04±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml | | pka | 11.21±0.46(Predicted) |
| | (Z)-3-oxo-N-[(3S)-2-oxooxolan-3-yl]hexadec-11-enamide Usage And Synthesis |
| Description | Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production, release, and detection of small diffusible signal molecules called autoinducers. The N-acylated homoserine lactones (AHLs) comprise one such class of autoinducers, each of which generally consists of a fatty acid coupled with homoserine lactone (HSL). Regulation of bacterial quorum sensing signaling systems to inhibit pathogenesis represents a new approach to antimicrobial therapy in the treatment of infectious diseases. AHLs vary in acyl group length (C4-C18), in the substitution of C3 (hydrogen, hydroxyl, or oxo group), and in the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signal specificity through the affinity of transcriptional regulators of the LuxR family. An unspecified positional and geometric isomer of 3-oxo-C16:1-(L)-HSL is produced by the F2/5 strain of A. vitis, the bacterium responsible for grape crown gall and its resulting loss of agricultural productivity. | | Uses | 3-Oxo-C16:1 could induce changes in root protein production in the model legume Medicago truncatula. 3-Oxo-C16:1 is an unsaturated 16-carbon AHL utilized by species such as S. meliloti and Agrobacterium vitus[1]. | | Definition | ChEBI: N-3-oxo-hexadec-11(Z)-enoyl-L-Homoserine lactone is a N-acyl-amino acid. | | References | [1] Andrew G Palmer, Plant responses to bacterial N-acyl L-homoserine lactones are dependent on enzymatic degradation to L-homoserine. ACS Chem Biol. 2014 Aug 15;9(8):1834-45. DOI:10.1021/cb500191a |
| | (Z)-3-oxo-N-[(3S)-2-oxooxolan-3-yl]hexadec-11-enamide Preparation Products And Raw materials |
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