- 3-Chloro-2-picoline
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- $9.80 / 1KG
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2020-01-03
- CAS:72093-03-9
- Min. Order: 1KG
- Purity: ≥98%
- Supply Ability: 20 tons
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| | 3-CHLORO-2-METHYLPYRIDINE Basic information |
| | 3-CHLORO-2-METHYLPYRIDINE Chemical Properties |
| Boiling point | 156.5±20.0 °C(Predicted) | | density | 1.150±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | pka | 3.67±0.10(Predicted) | | Appearance | Colorless to light yellow Liquid |
| | 3-CHLORO-2-METHYLPYRIDINE Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 3-chloro-2-methylpyridine from 3-amino-2-methylpyridine: 54 g of 3-amino-2-methylpyridine was slowly added to 130 g of concentrated hydrochloric acid (36-38% mass fraction). Subsequently, hydrogen chloride gas was passed to saturation and 222.45 g of phosphoryl chloride and 90 g of nitric acid at 70% mass concentration were added dropwise at 20-25°C. The reaction was carried out with continuous stirring and strict stirring. The reaction was carried out with continuous stirring and under strict temperature control. After completion of the reaction, 57.3 g of 3-chloro-2-methylpyridine was obtained in 89% yield and 99% purity after post-treatment. | | References | [1] Patent: CN105061300, 2018, B. Location in patent: Paragraph 0020; 0021 |
| | 3-CHLORO-2-METHYLPYRIDINE Preparation Products And Raw materials |
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