L(-)-Pipecolinic acid

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Products Intro: Product Name:L-Piperidine-2-carboxylic acid
CAS:3105-95-1
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Products Intro: Product Name:L-pipecolate
CAS:3105-95-1
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Products Intro: Product Name:L(-)-Pipecolinic acid
CAS:3105-95-1
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Products Intro: Product Name:L(-)-Pipecolinic acid
CAS:3105-95-1
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Products Intro: Product Name:L(-)-Pipecolinic acid
CAS:3105-95-1
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L(-)-Pipecolinic acid manufacturers

  • L-Pipecolic acid
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  • 2026-01-12
  • CAS:3105-95-1
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  • Purity: 99.93%
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  • L(-)-Pipecolinic acid
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  • 2025-06-27
  • CAS:3105-95-1
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  • L(-)-Pipecolinic acid
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  • 2025-05-26
  • CAS:3105-95-1
  • Min. Order: 1kg
  • Purity: 0.99
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L(-)-Pipecolinic acid Basic information
Description
Product Name:L(-)-Pipecolinic acid
Synonyms:RARECHEM BK PT F201;(S)-(-)-2-PIPERIDINECARBOXYLIC ACID;(S)-2-PIPERIDINECARBOXYLIC ACID;S-(-)-PIPECOLINIC ACID;(S)-(-)-PIPECOLIC ACID;(S)-PIPECOLIC ACID;(S)-PIPERIDINE-2-CARBOXYLIC ACID;PIP-OH
CAS:3105-95-1
MF:C6H11NO2
MW:129.16
EINECS:221-462-1
Product Categories:Chiral Compound;Chiral Reagents;Heterocycles;chiral;Chiral Reagent;Amino Acids and Derivatives;Pyridines;Amino Acids & Derivatives;Intermediates
Mol File:3105-95-1.mol
L(-)-Pipecolinic acid Structure
L(-)-Pipecolinic acid Chemical Properties
Melting point 272 °C(lit.)
alpha -27.5 º (c=5, H2O 24 ºC)
Boiling point 239.22°C (rough estimate)
density 1.1426 (rough estimate)
refractive index -27 ° (C=4, H2O)
storage temp. 2-8°C
solubility Water: Soluble
pka2.28(at 25℃)
form Fine Crystalline Powder
color White
Optical Rotation[α]25/D 26.4°, c = 1 in H2O
Water Solubility soluble
Merck 14,7458
BRN 81093
InChI1S/C6H11NO2/c8-6(9)5-3-1-2-4-7-5/h5,7H,1-4H2,(H,8,9)/t5-/m0/s1
InChIKeyHXEACLLIILLPRG-YFKPBYRVSA-N
SMILESOC(=O)[C@@H]1CCCCN1
CAS DataBase Reference3105-95-1(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36-24/25
WGK Germany 3
TSCA No
HS Code 29339900
Storage Class11 - Combustible Solids
Hazard ClassificationsEye Irrit. 2
Skin Irrit. 2
STOT SE 3
MSDS Information
ProviderLanguage
L(-)-Pipecolinic acid English
ACROS English
SigmaAldrich English
ALFA English
L(-)-Pipecolinic acid Usage And Synthesis
DescriptionL-Pipecolinic acid is involved in synaptic transmission in the central nervous system. It is also used as pharmaceutical intermediate. It is a lysine metabolite; defect in its catabolism is involved in hyperpipecolic acidemia, cerebro-hepato-renal syndrome, neonatal onset adrenoleukodystrophy, and infantile Refsum disease. It can be associated with some forms of epilepsy. CRYM, a taxon-specific crystallin protein that also binds thyroid hormones, is involved in the pipecolic acid pathway.
Chemical Propertieswhite to light yellow crystal powde
UsesPipecolic acid is involved in synaptic transmission in the central nervous system. The l-form occurs in plants.
UsesL-Pipecolinic acid is involved in synaptic transmission in the central nervous system. It is also used as pharmaceutical intermediate.
DefinitionChEBI: A pipecolate that is the conjugate acid of L--pipecolic acid.
General DescriptionOccurs in seeds, malt, edible mushrooms, fruits, etc.
Biochem/physiol ActionsL-pipecolic acid is implicated in Zellweger syndrome. Pipecolic acid is also a plant defence metabolite. It is a signaling compound essential for systemic acquired resistance (SAR).
Purification MethodsIt crystallises from water. The (±)-picrate has m 158-159o (from EtOH or C6H6). [Beilstein 22 H 7, 22 III/IV 97, 22/1 V 220.] The R(+)-enantiomer [1723-00-8] has m 277o(dec) and [] D 20 +27o (c 4, H2O), and the S(-)-enantiomer [3105-95-1] has m 277o(dec) and [] D 20 -26o (c 4, H2O).[cf p 603, Beilstein 22 III/IV 96, 22/1 V 220.]
L(-)-Pipecolinic acid Preparation Products And Raw materials
Preparation ProductsRopivacaine-->1-METHYLPIPERIDINE-2-CARBOXYLIC ACID HYDROCHLORIDE-->2-Piperidinecarboxylic acid, ethyl ester, (2S)-
Tag:L(-)-Pipecolinic acid(3105-95-1) Related Product Information
Folic acid DROPERIDOL Stearic acid Triacetonediamine Haloperidol Ethyl 2-(Chlorosulfonyl)acetate Citric acid 2,2,6,6-Tetramethyl-4-piperidinol Ascoric Acid Diphenoxylate D-1-CBZ-PIPECOLINIC ACID,N-FMOC-(R)-PIPECOLINIC ACID,FMOC-D-HOMOPROLINE,N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-D-HOMOPROLINE (S)-1-Boc-piperidine-2-carboxylic acid FMOC-L-PIPECOLIC ACID PIPECOLINIC ACID,DL-HOMOPROLINE,DL-Pipecolinic acid,2-PIPERIDINECARBOXYLIC ACID , DL-PIPECOLINIC ACID,Pipecolinic acid/Piperidine-2-carboxylic acid N-ALPHA-T-BUTOXYCARBONYL-DL-HOMOPROLINE,BOC-DL-HOMOPROLINE (R)-(+)-N-Boc-2-piperidinecarboxylic acid DL-Pipecolinic acid DL-HOMOPROLINE ETHYL ESTER,(±)-Ethyl piperidine-2-carboxylate, DL-Homoproline ethyl ester,PIPECOLINIC ACID ETHYL ESTER

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