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| | 4-(METHYLSULFONYL)PHENYLBORONIC ACID Basic information |
| | 4-(METHYLSULFONYL)PHENYLBORONIC ACID Chemical Properties |
| Melting point | 275-277 °C | | Boiling point | 445.5±51.0 °C(Predicted) | | density | 1.39±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | soluble in Methanol | | form | Powder | | pka | 7.22±0.10(Predicted) | | color | Off-white | | InChI | 1S/C7H9BO4S/c1-13(11,12)7-4-2-6(3-5-7)8(9)10/h2-5,9-10H,1H3 | | InChIKey | VDUKDQTYMWUSAC-UHFFFAOYSA-N | | SMILES | CS(=O)(=O)c1ccc(cc1)B(O)O | | CAS DataBase Reference | 149104-88-1(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 37/39-26-24/25-22 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29163990 | | Storage Class | 11 - Combustible Solids |
| | 4-(METHYLSULFONYL)PHENYLBORONIC ACID Usage And Synthesis |
| Chemical Properties | Off-white powder | | Uses | 4-(Methylsulfonyl)phenylboronic Acid is a heteroaryl boronic acid that was tested for their in vitro hormone-sensitive lipase inhibitory properties. | | Uses | 4-(Methanesulfonyl)phenylboronic acid may be used as reagent for:
- sequential Suzuki cross-coupling reactions
- Copper-catalyzed oxidative trifluoromethylthiolation of aryl boronic acids
- directed metalation and regioselective functionalization of 3-bromofuran and related heterocycles
- Barton-Zard pyrrole cyclocondensations and Baeyer-Villiger oxidations
- diplar cycloaddition and palladium-catalyzed cross-coupling processes
- continuous flow Suzuki reactions for odanacatib intermediate synthesis
Reagent used in Preparation of
- diarylaminopyridines as potential anti-malarial agents
- hydropyranopyrazine via chloropyrazinecarboxaldehyde and olefination
- biaryl sulfone derivatives as antagonists of the histamine H3 receptor
- novel kinase inhibitor scaffolds with potential antitumor effects
- Hepatitis C virus inhibition activity of N-hydroxyisoquinoline di
| | General Description | Contains varying amounts of anhydride |
| | 4-(METHYLSULFONYL)PHENYLBORONIC ACID Preparation Products And Raw materials |
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