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| | TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID Basic information |
| | TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID Chemical Properties |
| Melting point | 111-112℃ | | Boiling point | 407.2±38.0 °C(Predicted) | | density | 1.182±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | form | Solid | | pka | 3.51±0.10(Predicted) | | color | White to off-white | | Optical Rotation | Consistent with structure | | CAS DataBase Reference | 3601-66-9(CAS DataBase Reference) |
| | TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID Usage And Synthesis |
| Uses | Boc-DL-Phg-OH is a Glycine.html" class="link-product" target="_blank">Glycine (HY-Y0966) derivative[1]. | | Synthesis | General procedure for the synthesis of BOC-L-phenylglycine from di-tert-butyl dicarbonate and 2-amino-2-phenylacetic acid: DL-2-phenylglycine (5.0 g, 33 mmol) was dissolved in 1 N NaOH solution (132 mL). Subsequently, di-tert-butyl dicarbonate (19.0 mL, 82.7 mmol) was added and the reaction mixture was stirred at room temperature until the reaction was complete. N-tert-butoxycarbonyl-DL-phenylglycine was isolated as a white solid (7.61 g, 92% yield) by appropriate post-processing steps. | | References | [1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368 |
| | TERT-BUTOXYCARBONYLAMINO-PHENYL-ACETIC ACID Preparation Products And Raw materials |
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