| Company Name: |
Sigma-Aldrich
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| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Anti-Glutamine Synthetase
Purity:IgG fraction of antiserum, buffered aqueous solution Package:100μL, 0.2mL Remarks:G2781
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| Company Name: |
Wuhan Chemstan Biotechnology Co., Ltd.
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| Tel: |
027-65317797 15926423062 |
| Email: |
422450190@qq.com |
| Products Intro: |
Product Name:Recombinant Human GLUL Protein, His Tag
Purity:90% as determined by SDS-PAGE Package:50ug;100ug
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Monoclonal Anti-GLUL antibody produced in mouse
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| Company Name: |
Elabscience Biotechnology Co Ltd
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| Tel: |
400999210 |
| Email: |
marketing@elabscience.cn |
| Products Intro: |
Product Name:Recombinant Human GLUL Protein (His Tag)
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| | ANTI-GLUTAMINE SYNTHETASE Basic information |
| | ANTI-GLUTAMINE SYNTHETASE Chemical Properties |
| storage temp. | −20°C | | form | buffered aqueous solution | | biological source | rabbit |
| WGK Germany | - | | Storage Class | 12 - Non Combustible Liquids |
| | ANTI-GLUTAMINE SYNTHETASE Usage And Synthesis |
| Uses | Anti-Glutamine Synthetase antibody has been used for the detection and localization of GS by immunoblotting and immunohistochemistry. | | General Description | Anti-Glutamine Synthetase is produced in rabbit using a synthetic peptide corresponding to the C-terminus of mouse glutamine synthetase (GS) conjugated to keyhole limpet hemocyanin (KLH) as immunogen. This sequence is identical in human, bovine, rat, hamster and pig GS, and highly conserved in chicken GS. GS is found in mammals as an octamer of identical 45 kDa subunits. It is localized in glial cells of various species. It is present in the brain primarily in astrocytes and in the retina in Muller glial cells that support neurons using glutamate as a neurotransmitter. GS is found in several brain regions including hippocampus, cerebral cortex, neostriatum and cerebellar granular layer, corresponding to sites with high glutamate receptor density. | | Biochem/physiol Actions | GLUL (glutamate-ammonia ligase) gene encodes an ATP-dependent enzyme that catalyzes the synthesis of glutamine from glutamate and ammonia (nitrogen source). It is a member of the glutamine synthetase family. It is an essential enzyme in glutamine neogenesis. It functions in detoxification of ammonia and glutamate, acid-base homeostasis, cell signaling, and cell proliferation. It has a role in proliferation of fetal skin fibroblasts. Defects in this gene are associated with congenital glutamine deficiency. Overexpression of this gene has been observed in some primary liver cancer samples. |
| | ANTI-GLUTAMINE SYNTHETASE Preparation Products And Raw materials |
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