| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
|
| | AB-FUBICA Basic information |
| Product Name: | AB-FUBICA | | Synonyms: | AB-FUBICA;eMolecules ID: 106667567;1H-Indole-3-carboxamide, N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-;N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-[(4-fluorophenyl)methyl]-1H-indole-3-carboxamide | | CAS: | 1801338-22-6 | | MF: | C21H22FN3O2 | | MW: | 367.42 | | EINECS: | | | Product Categories: | | | Mol File: | 1801338-22-6.mol |  |
| | AB-FUBICA Chemical Properties |
| Boiling point | 663.1±50.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | form | A neat solid | | pka | 13.25±0.46(Predicted) |
| | AB-FUBICA Usage And Synthesis |
| Description | AB-FUBICA (Item No. 18758) is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB). It is an indole-based CB with the structural groups found in AB-FUBINACA . The physiological and toxicological properties of this compound are not known. This product is intended for research and forensic applications. | | Uses | AB-FUBICA (Compound 13) is a CB1 and CB2 receptor agonist that activates G-protein coupled inwardly rectifying potassium channels (GIRK) by binding to CB1 and CB2 receptors, displaying notable cannabinoid-like activity. AB-FUBICA has EC50 values of 21 nM for CB1 and 15 nM for CB2. AB-FUBICA may be suitable for studying pain management, neurodegenerative diseases, and inflammation-related mechanisms[1]. | | IC 50 | CB1: 21 nM (EC50); CB2: 15 nM (EC50) | | References | [1] Banister SD, et al. Pharmacology of Indole and Indazole Synthetic Cannabinoid Designer Drugs AB-FUBINACA, ADB-FUBINACA, AB-PINACA, ADB-PINACA, 5F-AB-PINACA, 5F-ADB-PINACA, ADBICA, and 5F-ADBICA. ACS Chem Neurosci. 2015 Sep 16;6(9):1546-59. DOI:10.1021/acschemneuro.5b00112 |
| | AB-FUBICA Preparation Products And Raw materials |
|