| Company Name: |
ChemShuttle, Inc. |
| Tel: |
0510-83588313-811 18800520310 |
| Email: |
sales@chemshuttle.com |
|
| | TBI-223 Basic information |
| Product Name: | TBI-223 | | Synonyms: | TBI-223;Carbamic acid, N-[[(5S)-3-[3-fluoro-4-(2-oxa-6-azaspiro[3.3]hept-6-yl)phenyl]-2-oxo-5-oxazolidinyl]methyl]-, methyl ester;methyl (S)-((3-(3-fluoro-4-(2-oxa-6-azaspiro[3.3]heptan-6-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)carbamate | | CAS: | 2071265-08-0 | | MF: | C17H20FN3O5 | | MW: | 365.36 | | EINECS: | | | Product Categories: | | | Mol File: | 2071265-08-0.mol |  |
| | TBI-223 Chemical Properties |
| Boiling point | 572.5±50.0 °C(Predicted) | | density | 1.45±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 11.69±0.46(Predicted) | | form | Solid | | color | White to off-white |
| | TBI-223 Usage And Synthesis |
| Uses | TBI-223 is an orally bioavailable oxazolidinone antibiotic and an antimicrobial. TBI-223 shows activity against Mycobacterium tuberculosis (Mtb)[1][2]. | | IC 50 | Oxazolidinone | | References | [1] Chauhan A, et al. Comprehensive review on mechanism of action, resistance and evolution of antimycobacterial drugs. Life Sci. 2021;274:119301. DOI:10.1016/j.lfs.2021.119301
[2] Motamen S, et al. Analysis of Approaches to Anti-tuberculosis Compounds. ACS Omega. 2020;5(44):28529-28540. Published 2020 Oct 27. DOI:10.1021/acsomega.0c03177 |
| | TBI-223 Preparation Products And Raw materials |
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