J104129

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J104129 Suppliers list
Company Name: BOC Sciences  
Tel: 1-631-485-4226; 16314854226
Email: info@bocsci.com
Company Name: Sigma-Aldrich  
Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Company Name: Energy Chemical  
Tel: 021-58432009 400-005-6266
Email: marketing@energy-chemical.com
Company Name: Beijing Biocreative Technology Co., Ltd.  
Tel: 15522676233
Email: 3007606172@qq.com
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310 15002144251
Email: marketing@tsbiochem.com
J104129 Basic information
Product Name:J104129
Synonyms:J104129;J104129 fumarate >=98% (HPLC)
CAS:257603-40-0
MF:C28H40N2O6
MW:500.64
EINECS:
Product Categories:
Mol File:257603-40-0.mol
J104129 Structure
J104129 Chemical Properties
storage temp. 2-8°C
solubility Soluble to 100 mM in DMSO and to 50 mM in ethanol
form powder
color white to beige
Optical Rotation[α]/D -6 to -8°, c = 1 in methanol
InChIKeyHUCQUCITPHOUAC-DSSYAJFBSA-N
SMILESO=C(O)/C=C/C(O)=O.CC(C)=CCCN(CC1)CCC1NC([C@](C2CCCC2)(O)C3=CC=CC=C3)=O
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
J104129 Usage And Synthesis
UsesJ 104129 Fumarate is a novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors.
Biochem/physiol ActionsJ104129 is a muscarinic M3 receptor antagonist greater than 100-fold selectivity for M3 over M2 receptors. Its Ki for M3 receptors = 4.2 nM compared to a Ki of 490 nM for M2 receptors. J-104129 showed potent bronchodilator activity in animal studies.
IC 50mAChR3: 4.2 nM (Ki); mAChR2: 490 nM (Ki)
storageStore at +4°C
J104129 Preparation Products And Raw materials
Tag:J104129(257603-40-0) Related Product Information
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