| Company Name: |
Alchem Pharmtech,Inc. |
| Tel: |
8485655694 |
| Email: |
sales@alchempharmtech.com |
| Products Intro: |
Product Name:(1R,3aR,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a,5a,5b,8,8,11a-Hexamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl acetate
CAS:1617-68-1
Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-36586
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- Lupeol acetate
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- $263.00 / 10mg
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2026-01-12
- CAS:1617-68-1
- Min. Order:
- Purity: 99.84%
- Supply Ability: 10g
- LUPEOL ACETATE
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- $1.00 / 1kg
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2019-07-06
- CAS:1617-68-1
- Min. Order: 1g
- Purity: 99%
- Supply Ability: 100KG
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| | LUPEOL ACETATE Basic information |
| Product Name: | LUPEOL ACETATE | | Synonyms: | LUPEOL ACETATE;3-Acetyllupeol;LUPEOL ACETATE(RG);3-O-Acetyllupeol;Lup-20(29)-en-3beta-ol, acetate;Lup-20(29)-en-3-ol, acetate, (3beta)-;Lup-20(29)-en-3-yl acetate;Lupenyl acetate | | CAS: | 1617-68-1 | | MF: | C32H52O2 | | MW: | 468.75 | | EINECS: | 216-575-8 | | Product Categories: | Tri-Terpenoids | | Mol File: | 1617-68-1.mol |  |
| | LUPEOL ACETATE Chemical Properties |
| Melting point | 218°C | | Boiling point | 502.7±19.0 °C(Predicted) | | density | 1.01±0.1 g/cm3(Predicted) | | form | Solid | | color | White to off-white | | InChIKey | ODSSDTBFHAYYMD-NVDDSYLUNA-N | | SMILES | [C@@]12(C)CC[C@@]3(C)CC[C@@H](C(=C)C)[C@]3([H])[C@@]1([H])CC[C@]1([H])[C@@]3(C)CC[C@H](OC(=O)C)C(C)(C)[C@]3([H])CC[C@@]21C |&1:0,4,8,12,14,18,20,24,32,36,r| | | LogP | 11.870 (est) |
| | LUPEOL ACETATE Usage And Synthesis |
| Uses | antiulcer | | Definition | ChEBI: Lupeol acetate is an organic molecular entity. It has a role as a metabolite. | | in vivo | Lupeol acetate (50 mg/kg; Intraperitoneal injection; 21 days) shows improvement in the mouse model of rheumatoid arthritis[3].
Lupeol acetate (10 mg/day; Oral administration; 60 days) plays an anti-fertility role in male rats[4]. | Animal Model: | DBA/1J mouse aged 8 weeks old with collagen-induced arthritis[3] | | Dosage: | 50 mg/kg | | Administration: | Intraperitoneal injection (i.p.); 21 days | | Result: | Reduced the incidence of arthritis and relieved symptoms of rheumatoid arthritis.
Significantly decreased clinical score and paw thickness.
Significantly lowered TNF-α and IL-1β levels in serum.
Inhibited inflammatory activity, significantly decreased the accumulation of 18F-FDG in the joints.
Reduced the infiltration of macrophages and bone erosion.
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| Animal Model: | Male albino rats of the Wistar strain aged 3.5-4 months old (170 and 200 g)[4] | | Dosage: | 10 mg/day | | Administration: | Oral administration (p.o.); 60 days | | Result: | Did not cause any significant change in the body weights, but significantly reduced in the weight of reproductive organs, i.e. testes, epididymides, seminal vesicle and ventral prostate.
Significantly declined testicular sperm count, epididymal sperm count and motility, which resulted in reduction of male fertility by 100%.
Interfered with spermatogenesis and significantly reduced most tubule cell types.
Significantly reduced biochemical parameters of tissues i.e. protein, sialic acid, glycogen and cholesterol content of testes and seminal vesicular fructose. |
| | IC 50 | COX-2 |
| | LUPEOL ACETATE Preparation Products And Raw materials |
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