| Company Name: |
Daicel Chiral Technologies (China)CO.,LTD
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| Tel: |
021-50460086-9 15921403865 |
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han_yajun@dctc.daicel.com |
| Products Intro: |
Product Name:4-((5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
CAS:2093386-39-9
Purity:95% Package:250MG;1G Remarks:209636
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| Company Name: |
Chengdu HuaNa Chemicals Co., Ltd.
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| Tel: |
028-86612776; 13699069380 |
| Email: |
515238037@qq.com |
| Products Intro: |
Product Name:4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dioneHCl
CAS:2093386-39-9
Purity:96% Package:100mg;100g Remarks:HN06
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| Company Name: |
Amatek Scientific Co. Ltd.
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| Tel: |
0512-56316828 |
| Email: |
info@amateksci.com |
| Products Intro: |
Product Name:4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
CAS:2093386-39-9
Purity:97% HPLC Package:1g;5g;25g;100g
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| | 4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Basic information |
| Product Name: | 4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl | | Synonyms: | 4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;1H-Isoindole-1,3(2H)-dione, 4-[(5-aminopentyl)amino]-2-(2,6-dioxo-3-piperidinyl)-;Thalidomide-4-NH-C5-NH2;4-[(5-aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione | | CAS: | 2093386-39-9 | | MF: | C18H22N4O4 | | MW: | 358.39 | | EINECS: | | | Product Categories: | | | Mol File: | 2093386-39-9.mol | ![4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Structure](CAS/20200331/GIF/2093386-39-9.gif) |
| | 4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Chemical Properties |
| Boiling point | 644.3±55.0 °C(Predicted) | | density | 1.373±0.06 g/cm3(Predicted) | | pka | 10.75±0.40(Predicted) |
| | 4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Usage And Synthesis |
| Uses | Thalidomide-NH-C5-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1]. | | IC 50 | Cereblon | | References | [1] Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine.?Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11. DOI:10.3389/fcell.2021.629326
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277 |
| | 4-[(5-Aminopentyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl Preparation Products And Raw materials |
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