2-Amino-6-methythio-9-(2'-deoxy-2'-fluooro-beta-D-arabinofuranosyl)-9H-purine
| 中文名称 | 2-Amino-6-methythio-9-(2'-deoxy-2'-fluooro-beta-D-arabinofuranosyl)-9H-purine |
|---|---|
| 中文同义词 | 化合物 2-AMINO-6-METHYTHIO-9-(2'-DEOXY-2'-FLUOORO-BETA-D- ARABINOFURANOSYL)-9H-PURINE |
| 英文名称 | 2-Amino-6-methythio-9-(2'-deoxy-2'-fluooro-beta-D-arabinofuranosyl)-9H-purine |
| 英文同义词 | 2-Amino-6-methythio-9-(2'-deoxy-2'-fluooro-beta-D-arabinofuranosyl)-9H-purine;9H-Purin-2-amine, 9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-(methylthio)-;2’-Deoxy-2’-fluoro-6-S-methyl-6-thio-ara-guanosine;2-Amino-6-methylthio-9-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-9H-purine;2-Amino-6-methythio-9-(2’-deoxy-2’-fluooro-beta-D-arabinofuranosyl)-9H-purine;(2R,3R,4S,5R)-5-(2-amino-6-(methylthio)-9H-purin-9-yl)-4-fluoro-2-(hydroxymethyl)tetrahydrofuran-3-ol |
| CAS号 | 109304-11-2 |
| 分子式 | C11H14FN5O3S |
| 分子量 | 315.32 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 109304-11-2.mol |
| 结构式 |  |
2-Amino-6-methythio-9-(2'-deoxy-2'-fluooro-beta-D-arabinofuranosyl)-9H-purine 性质
| 沸点 | 700.0±70.0 °C(Predicted) |
|---|---|
| 密度 | 1.92±0.1 g/cm3(Predicted) |
| 酸度系数(pKa) | 12.57±0.70(Predicted) |
2’-Deoxy-2’-fluoro-6-S-Methyl-6-thio-ara-guanosine 是一种嘌呤核苷类似物。嘌呤核苷类似物具有广泛的抗肿瘤活性，靶向惰性淋巴系统恶性肿瘤。这一过程中的抗癌机制依赖于抑制 DNA 合成，诱导细胞凋亡 (apoptosis) 等。