Azido-PEG3-CH2CO2-NHS manufacturers
- Azido-PEG3-NHS ester
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- $87.00 / 10mg
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2026-04-22
- CAS:1092654-47-1
- Min. Order:
- Purity:
- Supply Ability: 10g
- N3-PEG3-CH2COO-NHS
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- $0.00 / 1g
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2026-02-05
- CAS:1092654-47-1
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 1g/bottle, 10g/bottle, 100g/bottle
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| | Azido-PEG3-CH2CO2-NHS Basic information |
| Product Name: | Azido-PEG3-CH2CO2-NHS | | Synonyms: | Azido-PEG3-CH2CO2-NHS;N3-PEG3-CH2COONHS;2,5-dioxopyrrolidin-1-yl 2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)acetate;Azido-PEG3-CH2COOH NHS Ester;N3-PEG3-CH2COONHS/Acetic acid, 2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-, 2,5-dioxo-1-pyrrolidinyl ester;Azido-PEG3-CH2COO-NHS ester;12-Azido-3,6,9-trioxadodecan-1-oic acid-NHS-ester;Azido-PEG-CHCO-NHS | | CAS: | 1092654-47-1 | | MF: | C12H18N4O7 | | MW: | 330.3 | | EINECS: | | | Product Categories: | | | Mol File: | 1092654-47-1.mol |  |
| | Azido-PEG3-CH2CO2-NHS Chemical Properties |
| storage temp. | Storage temp. -20°C | | solubility | Soluble in Water, DMSO, DCM, DMF | | form | Liquid | | color | Colorless to light yellow |
| | Azido-PEG3-CH2CO2-NHS Usage And Synthesis |
| Description | Azido-PEG3-CH2CO2-NHS consist of azide and NHS ester moieties The azide(N3) group is reactive with alkynes, BCN and DBCO via Click Chemistry to yield a stable triazole linkage. The NHS ester can label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. | | Uses | Azido-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG3-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | | IC 50 | PEGs | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
| | Azido-PEG3-CH2CO2-NHS Preparation Products And Raw materials |
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