Facinicline

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Facinicline Suppliers list
Company Name: BOC Sciences  
Tel: 16314854226; +8616314854226
Email: inquiry@bocsci.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354;
Email: support@targetmol.com

Facinicline manufacturers
Facinicline Basic information
Product Name:Facinicline
Synonyms:Facinicline;Facinicline (free base);MEM-3454;R-3487;RO-5313534;1H-Indazole-3-carboxamide, N-(3S)-1-azabicyclo[2.2.2]oct-3-yl-
CAS:677306-35-3
MF:C15H18N4O
MW:270.33
EINECS:
Product Categories:
Mol File:677306-35-3.mol
Facinicline Structure
Facinicline Chemical Properties
Boiling point 558.8±30.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
pka12.44±0.40(Predicted)
Safety Information
MSDS Information
Facinicline Usage And Synthesis
UsesFacinicline (RG3487) is an orally active nicotinic α7 receptor partial agonist, with a Ki of 6 nM for α7 human nAChR. Facinicline improves cognition and sensorimotor gating in rodents. Facinicline hydrochloride shows high affinity (antagonist) to 5-HT3Rs with a Ki value of 1.2 nM[1].
References[1] Tanya L Wallace, et al. RG3487, a Novel Nicotinic α7 Receptor Partial Agonist, Improves Cognition and Sensorimotor Gating in Rodents. J Pharmacol Exp Ther. 2011 Jan;336(1):242-53. DOI:10.1124/jpet.110.171892
Facinicline Preparation Products And Raw materials
Tag:Facinicline(677306-35-3) Related Product Information
5-Hydroxytryptophan 3-(2,4-dimethoxybenzylidene)anabaseine Puerarin Carbachol Dihydroergotamine mesylate Choline chloride