MK-0493

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MK-0493 Suppliers list
Company Name: BOC Sciences  
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Email: inquiry@bocsci.com
Company Name: TargetMol Chemicals Inc.  
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Company Name: TargetMol Chemicals Inc.  
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MK-0493 Basic information
Product Name:MK-0493
Synonyms:MK-0493 HCl;MK0493 HCl,MK 0493 HCl
CAS:455957-71-8
MF:C30H39Cl2F2N3O2
MW:582.56
EINECS:
Product Categories:
Mol File:455957-71-8.mol
MK-0493 Structure
MK-0493 Chemical Properties
form Solid
Safety Information
MSDS Information
MK-0493 Usage And Synthesis
UsesMK-0493 hydrochloride is a potent, orally active and selective agonist of the melanocortin receptor 4 (MC4R), demonstrating significant reductions in energy intake[1].
References[1] Krishna R, etal. Potent and selective agonism of the melanocortin receptor 4 with MK-0493 does not induce weight loss in obese human subjects: energy intake predicts lack of weight loss efficacy. Clin Pharmacol Ther. 2009 Dec;86(6):659-66. DOI:10.1038/clpt.2009.167
[2] Sezen SF, et al. Intracavernosal pressure monitoring in mice: responses to electrical stimulation of the cavernous nerve and to intracavernosal drug administration. J Androl. 2000 Mar-Apr;21(2):311-5. PMID:10714826
[3] Hong Q, et al. Discovery of a piperazine urea based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor partial agonist. Bioorg Med Chem Lett. 2011 Apr 15;21(8):2330-4. DOI:10.1016/j.bmcl.2011.02.090
MK-0493 Preparation Products And Raw materials
Tag:MK-0493(455957-71-8) Related Product Information
D-Prolinamide, N-acetyl-L-norleucyl-L-α-aspartyl-L-prolyl-3-(2-naphthalenyl)-D-alanyl-L-arginyl-L-tryptophyl-L-lysyl-D-valyl-, (2→7)-lactam Tetracosactide acetate ALPHA-MSH Msg 606 JNJ-10229570 HS024 TFA