| Company Name: |
Sigma-Aldrich
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021-61415566 800-8193336 |
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orderCN@merckgroup.com |
| Products Intro: |
Product Name:Methoprene acid
CAS:53092-52-7
Purity:>=98% (TLC) Package:5mg Remarks:M6682
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| Company Name: |
Energy Chemical
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| Tel: |
021-58432009 400-005-6266 |
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marketing@energy-chemical.com |
| Products Intro: |
Product Name:Methoprene acid >=98% (TLC)
CAS:53092-52-7
Purity:NULL Package:5mg Remarks:NULL
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| Company Name: |
Shanghai Weiyite Biotechnology Co., Ltd
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| Tel: |
15317051735 |
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zhaojing@wytsci.com |
| Products Intro: |
Product Name:S Methoprene Acid
CAS:53092-52-7
Purity:95% HPLC Package:1mg;2.5mg;5mg;10mg;25mg;50mg;100mg
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| | METHOPRENE ACID Basic information |
| Product Name: | METHOPRENE ACID | | Synonyms: | 11-methoxy-3,7,11-trimethyl-,(e,e)-(+/-)-4-dodecadienoicacid;(2E,4E)-(±)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid;(+-)-(2E,4E)-11-Methoxy-3,7,11-trimethyl-2,4-dodecadienoic acid;(2E,4E)-(1)-11-Methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid;2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, (2E,4E)-;Einecs 258-355-4;Methoprene acid >=98% (TLC);S Methoprene Acid | | CAS: | 53092-52-7 | | MF: | C16H28O3 | | MW: | 268.39 | | EINECS: | 258-355-4 | | Product Categories: | | | Mol File: | 53092-52-7.mol |  |
| | METHOPRENE ACID Chemical Properties |
| Boiling point | 394.1±25.0 °C(Predicted) | | density | 0.954±0.06 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO or Ethanol | | form | Pale yellow oil. | | pka | 4.96±0.33(Predicted) | | color | Colorless | | Stability: | Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. | | InChI | 1S/C16H28O3/c1-13(10-7-11-16(3,4)19-5)8-6-9-14(2)12-15(17)18/h6,9,12-13H,7-8,10-11H2,1-5H3,(H,17,18)/b9-6+,14-12+ | | InChIKey | MNYBEULOKRVZKY-TZOAMJEDSA-N | | SMILES | COC(C)(C)CCCC(C)C\C=C\C(C)=C\C(O)=O | | EPA Substance Registry System | 2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, (2E,4E)- (53092-52-7) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | TSCA | TSCA listed | | Storage Class | 10 - Combustible liquids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | METHOPRENE ACID Usage And Synthesis |
| Description | Methoprene Acid (53093-52-7) is an analog of insect juvenile hormone which acts as an insect growth regulator. Binds directly and selectively to the retinoid X receptor (RXR) acting as a transcriptional activator in both insect and mammalian cells with no activity at RAR.1Negatively regulates thrombosis and hemostasis.2Induces neurosteroid biosynthesis in human glial GI-1 cells.3Increases the expression of the brown-fat-uncoupling-protein-1 gene (ucp-1).4 | | Uses | Methoprene Acid is an analog of insect juvenile hormone which acts as an insect growth regulator. | | Definition | ChEBI: 11-methoxy-3,7,11-trimethyldodeca-2,4-dienoic acid is a sesquiterpenoid. | | General Description | Retinoic acid receptor (RXR) agonist used in gene regulation research. Analog of juvenile hormone, an insect growth hormone. | | Biochem/physiol Actions | Demethylation, oxidative cleavage, hydrolysis, photodegradation and degradation of methoprene by microorganism results in methoprene acid and other metabolites. Methoprene acid is an insect growth regulator, and is known to control ecdysteroid signaling during development and metamorphism. It is thus used to control larval growth in insects such as mosquitoes, cigarette beetles, fleas and fire ants. | | References | [1] M A HARMON. Activation of mammalian retinoid X receptors by the insect growth regulator methoprene.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1995, 92 13: 6157-6160. DOI:10.1073/pnas.92.13.6157
[2] AMANDA J UNSWORTH. RXR Ligands Negatively Regulate Thrombosis and Hemostasis.[J]. Arteriosclerosis, Thrombosis, and Vascular Biology, 2017, 37 5: 812-822. DOI:10.1161/atvbaha.117.309207
[3] AKIRA KUSHIDA Hiroomi T. Retinoic acids induce neurosteroid biosynthesis in human glial GI-1 Cells via the induction of steroidogenic genes.[J]. Journal of biochemistry, 2009, 146 6: 917-923. DOI:10.1093/jb/mvp142
[4] R. ALVAREZ. Both retinoic-acid-receptor- and retinoid-X-receptor-dependent signalling pathways mediate the induction of the brown-adipose-tissue-uncoupling-protein-1 gene by retinoids.[J]. The Ukrainian Biochemical Journal, 2000, 1 1: 91-97. DOI:10.1042/bj3450091 |
| | METHOPRENE ACID Preparation Products And Raw materials |
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