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| | ACAT1 antibody Chemical Properties |
| | ACAT1 antibody Usage And Synthesis |
| Source | Rabbit | | Applications | The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Recommended starting dilution is 1:1000. | | Reactivity | Human;Mouse;Rat | | Immunogen | Anti-human ACAT1 mAb, clone PAT2C5A, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ACAT1 protein. | | Background | Acetoacetyl-CoA thiolase (ACAT1) is an enzyme member of the membrane-bound acyltransferase family and Sterol o-acyltransferase subfamily. The ACAT1 enzyme catalyzes the reversible formation of acetoacetyl-CoA from 2 molecules of acetyl-CoA. ACAT1 plays a part in lipoprotein compilation and dietary cholesterol absorption. Added to its acyltransferase activity, ACAT1 acts as a ligase. | | References | [1] Balasse, E.O. and Féry, F. (1989) Diabetes Metab Rev 5, 247-70.
[2] Pohl, J. et al. (2006) Eur J Gastroenterol Hepatol 18, 69-74.
[3] Haapalainen, A.M. et al. (2007) Biochemistry 46, 4305-21.
[4] Fan, J. et al. (2014) Mol Cell 53, 534-48.
[5] Fan, J. et al. (2016) Mol Cell 64, 859-874. |
| | ACAT1 antibody Preparation Products And Raw materials |
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