(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine

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Company Name: Changzhou Xuanye Technology Co., Ltd  
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(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine manufacturers

  • PRMT4-IN-1
  • PRMT4-IN-1 pictures
  • $2800.00
  • 2026-04-21
  • CAS:912970-79-7
  • Purity:
  • Supply Ability: 10g
(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine Basic information
Product Name:(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine
Synonyms:(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine;1-Piperidineethanamine, 4-[3-fluoro-2-(2-methoxyphenyl)-1H-indol-5-yl]-N-methyl-;PRMT4-IN-1;2-(4-(3-Fluoro-2-(2-methoxyphenyl)-1H-indol-5-yl)piperidin-1-yl)-N-methylethan-1-amine
CAS:912970-79-7
MF:C23H28FN3O
MW:381.49
EINECS:
Product Categories:
Mol File:912970-79-7.mol
(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine Structure
(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine Chemical Properties
Boiling point 535.4±50.0 °C(Predicted)
density 1.154±0.06 g/cm3(Predicted)
pka15.37±0.30(Predicted)
Safety Information
MSDS Information
(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine Usage And Synthesis
UsesPRMT6-IN-2 (compound 2) is a dual inhibitor of protein arginine methyltransferase PRMT6 and CARM1 with an IC50 of 30 nM. PRMT6 is abnormally expressed in many cancer cells, and PRMT6-IN-2-based derivatives have potential anticancer activity.
References[1] Discovery of a Potent Class I Protein Arginine Methyltransferase Fragment Inhibitor
(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine Preparation Products And Raw materials
Tag:(2-{4-[3-Fluoro-2-(2-methoxy-phenyl)-1H-indol-5-yl]-piperidin-1-yl}-ethyl)-methyl-amine(912970-79-7) Related Product Information
EPZ015666 GSK-3326595 UNC-0642 UNC0638 DS-3201 MRTX-1719