| Company Name: |
Twochem Co.Ltd |
| Tel: |
021-021-58111628 15800915896 |
| Email: |
sales@twochem.com |
VBIT-12 manufacturers
- VBIT-12
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-
2026-08-11
- CAS:2089227-65-4
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kg
- VBIT-12
-
- $42.00
-
2026-07-27
- CAS:2089227-65-4
- Purity: 99.85%
- Supply Ability: 10g
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| | VBIT-12 Basic information |
| Product Name: | VBIT-12 | | Synonyms: | VBIT-12;Glycine, N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-;VBIT 12,VBIT12;N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl]-glycine;VBIT-12, 10 mM in DMSO;VBIT-12 ，S8936;N-[[1-(1-naphthalenylmethyl)-4-(phenylamino)-4-piperidinyl]carbonyl] | | CAS: | 2089227-65-4 | | MF: | C25H27N3O3 | | MW: | 417.5 | | EINECS: | 604-604-1 | | Product Categories: | | | Mol File: | 2089227-65-4.mol |  |
| | VBIT-12 Chemical Properties |
| Boiling point | 698.0±55.0 °C(Predicted) | | density | 1.286±0.06 g/cm3(Predicted) | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 15 mg/ml | | form | A crystalline solid | | pka | 3.65±0.10(Predicted) | | color | White to off-white |
| | VBIT-12 Usage And Synthesis |
| Uses | VBIT-12 is a potent VDAC1 inhibitor. VBIT-12 directly interacts with VDAC1 and prevents VDAC1 oligomerization, and thus inhibits apoptotic action of VDAC1[1]. | | References | [1] Shoshan-Barmatz V, et al. VDAC1, mitochondrial dysfunction, and Alzheimer's disease. Pharmacol Res. 2018 May;131:87-101. DOI:10.1016/j.phrs.2018.03.010 |
| | VBIT-12 Preparation Products And Raw materials |
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