| Company Name: |
Sichuan Wei Keqi Biological Technology Co., Ltd.
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| Tel: |
028-81700200 18116577057 |
| Email: |
3003855609@qq.com |
| Products Intro: |
Product Name:PROTACBET-bindingmoiety1
CAS:2093387-77-8
Purity:98% Package:5mg；10mg；20mg；50mg；100mg；200mg；500mg；1g
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:PROTAC BET-binding moiety 1
CAS:2093387-77-8
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
| Company Name: |
Kaifeng Mingren Pharmaceutical Co.,LTD
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| Tel: |
0371-65741762 |
| Email: |
sales@hasunny.com |
| Products Intro: |
Product Name:PROTAC BET-binding moiety 1
CAS:2093387-77-8
Purity:98% Package:10mg
|
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| | 9H-Pyrimido[4,5-b]indole-2-carboxylic acid, 4-[(3-cyclopropyl-1-ethyl-1H-pyrazol-5-yl)amino]-7-(3,5-dimethyl-4-isoxazolyl)-6-methoxy- Basic information |
| | 9H-Pyrimido[4,5-b]indole-2-carboxylic acid, 4-[(3-cyclopropyl-1-ethyl-1H-pyrazol-5-yl)amino]-7-(3,5-dimethyl-4-isoxazolyl)-6-methoxy- Chemical Properties |
| Boiling point | 783.1±70.0 °C(Predicted) | | density | 1.59±0.1 g/cm3(Predicted) | | form | Solid | | pka | 0.70±0.30(Predicted) | | color | Light yellow to yellow |
| | 9H-Pyrimido[4,5-b]indole-2-carboxylic acid, 4-[(3-cyclopropyl-1-ethyl-1H-pyrazol-5-yl)amino]-7-(3,5-dimethyl-4-isoxazolyl)-6-methoxy- Usage And Synthesis |
| Uses | PROTAC BET-binding moiety 1 is a key intermediate for the synthesis of high-affinity BET inhibitors[1]. | | References | [1] Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481. DOI:10.1021/acs.jmedchem.6b01816 |
| | 9H-Pyrimido[4,5-b]indole-2-carboxylic acid, 4-[(3-cyclopropyl-1-ethyl-1H-pyrazol-5-yl)amino]-7-(3,5-dimethyl-4-isoxazolyl)-6-methoxy- Preparation Products And Raw materials |
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