Brr2 Inhibitor C9 manufacturers
- Brr2-IN-3
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- $40.00 / 1mg
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2026-01-26
- CAS:2104030-82-0
- Min. Order:
- Purity: 99.26%
- Supply Ability: 10g
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| | Brr2 Inhibitor C9 Basic information |
| Product Name: | Brr2 Inhibitor C9 | | Synonyms: | Brr2 Inhibitor C9;Pyrido[4,3-d]pyrimidine-2,7(1H,3H)-dione, 4,6-dihydro-6-(phenylmethyl)-3-[3-(5-thiazolylmethoxy)phenyl]-;GUN30820;Brr2 Inhibitor 9;Brr2-IN-3;6-Benzyl-3-(3-(thiazol-5-ylmethoxy)phenyl)-3,4-dihydropyrido[4,3-d]pyrimidine-2,7(1H,6H)-dione;Inhibitor,selective,dose-dependent,Brr2IN3,inhibit,helicase,Brr-2-IN-3,targeting,potent,allosteric,Brr2 IN 3;Brr2-IN-3, 10 mM in DMSO | | CAS: | 2104030-82-0 | | MF: | C24H20N4O3S | | MW: | 444.51 | | EINECS: | | | Product Categories: | | | Mol File: | 2104030-82-0.mol |  |
| | Brr2 Inhibitor C9 Chemical Properties |
| Boiling point | 777.4±60.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO : 50 mg/mL (112.48 mM; Need ultrasonic) | | form | Solid | | pka | 11.84±0.20(Predicted) | | color | White to off-white |
| | Brr2 Inhibitor C9 Usage And Synthesis |
| Uses | Brr2-IN-3 is a potent and selective Brr2 helicase allosteric Inhibitor. Brr2-IN-3 inhibits helicase activity in dose-dependent manner with an IC50 value of 1.3 μM[1]. | | References | [1] Iwatani-Yoshihara M, et al. Discovery of Allosteric Inhibitors Targeting the Spliceosomal RNA Helicase Brr2. J Med Chem. 2017;60(13):5759-5771. DOI:10.1021/acs.jmedchem.7b00461 |
| | Brr2 Inhibitor C9 Preparation Products And Raw materials |
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