pNPS-DHA manufacturers
- pNPS-DHA
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- $113.00
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2026-05-11
- CAS:2454246-25-2
- Purity:
- Supply Ability: 10g
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| | pNPS-DHA Basic information |
| Product Name: | pNPS-DHA | | Synonyms: | pNPS-DHA;pNPS DHA,pNPSDHA;4,7,10,13,16,19-Docosahexaenamide, N-[(4-nitrophenyl)sulfonyl]-, (4Z,7Z,10Z,13Z,16Z,19Z)-;(4Z,7Z,10Z,13Z,16Z,19Z)-N-[(4-nitrophenyl)sulfonyl]docosa-4,7,10,13,16,19-docosahexaenamide | | CAS: | 2454246-25-2 | | MF: | C28H36N2O5S | | MW: | 512.66 | | EINECS: | | | Product Categories: | | | Mol File: | 2454246-25-2.mol |  |
| | pNPS-DHA Chemical Properties |
| density | 1.121±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Methyl Acetate: Soluble | | pka | 4.32±0.10(Predicted) |
| | pNPS-DHA Usage And Synthesis |
| Uses | pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM[1]. | | Biological Activity | pNPS-DHA is an arylamide derivative of docosahexaenoyl ethanolamide that has anti-allergic activity.1 It inhibits degranulation of RBL-2H3 mast cells (IC50 = 15 μM). pNPS-DHA (1,000 mg/kg) inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) in mice. | | References | 1.Kim, I.-H., Kanayama, Y., Nishiwaki, H., et al.Structure-activity relationships of fish oil derivatives with anti-allergic activity in vitro and in vivoJ. Med. Chem.62(21)9576-9592(2019) |
| | pNPS-DHA Preparation Products And Raw materials |
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