D-(+)-Norephedrine

D-(+)-Norephedrine Basic information
Product Name:D-(+)-Norephedrine
Synonyms:(1S,2R)-(+)-2-AMINO-1-PHENYL-1-PROPANOL;(1S,2R)-2-AMINO-1-PHENYL-1-PROPANOL;(1S,2R)-(+)-PHENYLPROPANOLAMINE;(1S,2R)-(+)-NOREPHEDRINE;D-(+)-NOREPHEDRINE;ERYTHRO-ALPHA-(1-AMINOETHYL)BENZYL ALCOHOL;(1S,2R)-(+)-Norephedrine [DD];D-(+)-Norephedrine [DD]
CAS:37577-28-9
MF:C9H13NO
MW:151.21
EINECS:628-077-1
Product Categories:Pharmaceutical Intermediates
Mol File:37577-28-9.mol
D-(+)-Norephedrine Structure
D-(+)-Norephedrine Chemical Properties
Melting point 51-54 °C(lit.)
alpha 40 º (c=7, 1M HCl)
Boiling point 288.1±20.0 °C(Predicted)
density 1.071±0.06 g/cm3(Predicted)
Fp >230 °F
storage temp. 2-8°C
pka12.07±0.45(Predicted)
Optical Rotation[α]20/D +40°, c = 7 in 1 M HCl
BRN 2802896
CAS DataBase Reference37577-28-9(CAS DataBase Reference)
NIST Chemistry Reference(1S,2r)-(+)-norephedrine(37577-28-9)
Safety Information
Hazard Codes Xn
Risk Statements 22-36/37/38
Safety Statements 26
WGK Germany 3
3-8-10
MSDS Information
ProviderLanguage
SigmaAldrich English
D-(+)-Norephedrine Usage And Synthesis
Uses(1S,2R)-(+)-Norephedrine Hydrochloride is used in preparation of pyrrolopyridines as ERK inhibitors useful in treatment of diseases.
DefinitionChEBI: (+)-norephedrine is an amphetamine that is propylbenzene substituted by a hydroxy group at position 1 and by an amino group at position 2 (the 1S,2R-stereoisomer). It is a member of amphetamines and a phenethylamine alkaloid.
D-(+)-Norephedrine Preparation Products And Raw materials
Raw materialsCATHINONE-->(1S,2S)-(-)-1-PHENYLPROPYLENE OXIDE-->CIS-BETA-METHYLSTYRENE-->TRANS-BETA-METHYLSTYRENE
Preparation ProductsL-(-)-Ephedrine
Tag:D-(+)-Norephedrine(37577-28-9) Related Product Information
ALTRENOGEST 1-Propanol Phenylhydrazine Betaine Glycine PHENYL VALERATE (1R,2S)-(-)-NOREPHEDRINE HYDROCHLORIDE,(IR,2S)-I-Norephedrine HCI D-METHAMPHETAMINE L-(-)-Ephedrine (-)-N-METHYLEPHEDRINE Ephedrine D-Ephedrine hydrochloride DL-Norephedrine hydrochloride (IS,2R)-d-Norephedrine HCI,(1S,2R)-(+)-NOREPHEDRINE HYDROCHLORIDE,D-(+)-NOREPHEDRINE HYDROCHLORIDE (+)-N-METHYLEPHEDRINE D-(+)-Norephedrine Ephedrine hydrochloride Benzyl (2S,3R)-(+)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate

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