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16314854226; +8616314854226 |
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| Company Name: |
BOC Sciences |
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16314854226 |
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info@bocsci.com |
(RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid manufacturers
- Cl-HIBO
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- $1980.00
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2026-05-11
- CAS:909400-43-7
- Purity:
- Supply Ability: 10g
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| | (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid Basic information |
| | (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid Chemical Properties |
| density | 1.66±0.1 g/cm3(Predicted) | | storage temp. | Store at RT | | pka | 2.26±0.10(Predicted) | | form | Powder | | Water Solubility | Soluble to 20 mM in water |
| | (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid Usage And Synthesis |
| Uses | The α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA receptor), a heterotetrameric transmembrane receptor, is found in various areas of the brain and mediates fast synaptic transmission in the central nervous system (1). Cl-HIBO (chloro-homoibotenic acid) is a subtype selective AMPA receptor agonist (2). | | Biological Activity | Subtype-selective and strongly desensitising AMPA receptor agonist; selective for GluR1 and GluR2 subunit-containing receptors (EC 50 values are 4.7, 1.7, 2700 and 1300 μ M for rat recombinant homomeric GluR1, 2, 3 and 4 receptors respectively). |
| | (RS)-2-Amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionic acid Preparation Products And Raw materials |
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