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| Product Name: | Glyceryl monothioglycolate | | Synonyms: | GLYCEROLMONOTHIOGLYCOLATE;Glycerol monomercaptoacetate;Mercaptoacetic acid monoester with 1,2,3-propanetriol;Acetic acid, 2-mercapto-, monoester with 1,2,3-propanetriol;Acetic acid, mercapto-, monoester with glycerol;Einecs 250-264-8;mercaptoacetic acid, monoester with propane-1,2,3-triol;GLYCERYL THIOGLYCOLATE | | CAS: | 30618-84-9 | | MF: | C5H10O4S | | MW: | 166.2 | | EINECS: | 250-264-8 | | Product Categories: | | | Mol File: | 30618-84-9.mol |  |
| | Glyceryl monothioglycolate Chemical Properties |
| | Glyceryl monothioglycolate Usage And Synthesis |
| Allergy symptoms |
Glyceryl mono thioglycolate has been recognized as a potential sensitizer and has been reported to cause allergic contact dermatitis in both hairdressers and clients. Hairdressers most commonly manifest their allergy as a hand dermatitis, whereas the clients most often have a dermatitis involving the scalp, face, ears, and neck. In preliminary patch testing, hair recently permanently woven with a solution containing glyceryl monothioglycolate produced positive results. These observations suggested that the permanent-waved hair may retain glyceryl monothioglycolate or a cross-reacting product. Positive reactions were seen in hair collected as long as 3 months after the permanent. This suggests that a glyceryl monothioglycolate-related allergen is retained in hair for up to 3 months after the permanent, which may explain the long-lasting dermatitis in clients sensitive to glyceryl monothioglycolate[1].
| | Description | Glyceryl monothioglycolate is an acid permanent wave
ingredient, which induces contact dermatitis in hairdressers. | | Uses | Glyceryl monothio-glycolate is a component in "acid" permanent waving formulations, mainly for use in hairdressing salons. | | Definition | ChEBI: Glyceryl monothioglycolate is a thioglycolate ester resulting from esterification of thioglycolic acid with glycerol. As a component of developer solutions in permanent wave products, it is the second most frequent allergen in hairdressers and avoidance of acid permanent waves is mandatory. It has a role as an allergen. | | Hazard | A mild skin and eye irritant | | Flammability and Explosibility | Non flammable | | Contact allergens | It is an acid permanent-wave ingredient, which induces
contact dermatitis in hairdressers. | | References | [1] Lynne H. Morrison M.D. , Frances J. Storrs M.D. “Persistence of an allergen in hair after glyceryl monothioglycolate—containing permanent wave solutions.” Journal of the American Academy of Dermatology 19 1 (1988): Pages 52-59. |
| | Glyceryl monothioglycolate Preparation Products And Raw materials |
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