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| | 5-Trans U-44069 Basic information |
| Product Name: | 5-Trans U-44069 | | Synonyms: | 9,11-DIDEOXY-9ALPHA, 11ALPHA-EPOXYMETHANO-PROSTA-5E,13E-DIEN-1-OIC ACID;DJKDIKIDYDXHDD-YTQMDITASA-N;5-Heptenoic acid, 7-[(1S,4R,5S,6R)-5-[(1E,3S)-3-hydroxy-1-octenyl]-2-oxabicyclo[2.2.1]hept-6-yl]-, (5E)- (9CI);5-Trans U-44069 | | CAS: | 330796-57-1 | | MF: | C21H34O4 | | MW: | 350.49 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 5-Trans U-44069 Chemical Properties |
| Boiling point | 519.7±35.0 °C(Predicted) | | density | 1.092±0.06 g/cm3(Predicted) | | solubility | DMF: >100 mg/ml (from U-46619); DMSO: >100 mg/ml (from U-46619); Ethanol: >100 mg/ml (from U-46619); PBS pH 7.2: >2 mg/ml (from U-46619) | | pka | 4.76±0.10(Predicted) |
| | 5-Trans U-44069 Usage And Synthesis |
| Description | 5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069 . It inhibits microsomal prostaglandin E2 synthase (mPGES) when used at a concentration of 10 μM.1 | | Uses | 5-trans U-44069 is the trans isomer of the thromboxane receptor agonist U-44069 (HY-121825). 5-trans U-44069 inhibits prostaglandin E2 synthase activity[1]. | | References | 1. Quraishi, O., Mancini, J.A., and Riendeau, D. Inhibition of inducible prostaglandin E2 synthase by 15-deoxy-Δ12,14-prostaglandin J2 and polyunsaturated fatty acids Biochem. Pharmacol. 63(6),1183-1189(2002). |
| | 5-Trans U-44069 Preparation Products And Raw materials |
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