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| | 1-Fluoropyridinium tetrafluoroborate Basic information |
| | 1-Fluoropyridinium tetrafluoroborate Chemical Properties |
| Melting point | 186-192 °C (lit.) | | storage temp. | Storage temp. 2-8°C | | form | Powder | | color | Off-white | | Sensitive | Moisture Sensitive | | BRN | 4281226 | | InChI | 1S/C5H5FN.BF4/c6-7-4-2-1-3-5-7;2-1(3,4)5/h1-5H;/q+1;-1 | | InChIKey | PIGQKECRKGMXRG-UHFFFAOYSA-N | | SMILES | F[B-](F)(F)F.F[n+]1ccccc1 | | CAS DataBase Reference | 107264-09-5(CAS DataBase Reference) |
| Hazard Codes | C | | Risk Statements | 34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 3 | | F | 9-21 | | Hazard Note | Moisture sensitive/Corrosive | | HazardClass | 8 | | PackingGroup | III | | HS Code | 29333990 | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Eye Dam. 1
Skin Corr. 1B |
| | 1-Fluoropyridinium tetrafluoroborate Usage And Synthesis |
| Chemical Properties | off-white powder | | Uses | 1-Fluoropyridine tetrafluoroborate is a pyridine organic compound, which can be used as an intermediate in pharmaceutical synthesis. | | General Description | 1-Fluoropyridinium tetrafluoroborate (N-Fluoropyridinium tetrafluoroborate), an N-fluorinated compound, is an electrophilic fluorinating reagent (containing N and F double bond). Controlled potential electrolysis of 1-fluoropyridinium tetrafluoroborate has been reported to afford pyridine, 2-fluoropyridine and 2-acetamidopyridine. | | Research | The products from the controlled potential electrolysis of 1-fluoropyridinium tetrafluoroborate were determined to be pyridine, 2-fluoropyridine, and 2-acetamidopyridine in yields. Loss of fluoride ion from the neutral radical in equilibrium with the dimer is believed to be the initial step in a multi-step mechanism, which results in the products observed from the controlled potential coulometry of 1-fluoropyridinium tetrafluoroborate. Catalytic fluorination/chlorination competition experiments of β-keto ester 5 were used to assess the relative fluorinating activity of various electrophilic NF reagents (containing an NF bond). SelectfluorTM ( F-TEDA; TEDA=triethylenediamine) reacts more than 100 times faster than 1-fluoropyridinium tetrafluoroborate[1-2]. | | References |
[1] Edward W Oliver, Dennis H Evans. “Electrochemical studies of six NF electrophilic fluorinating reagents.” Journal of Electroanalytical Chemistry 474 1 (1999): Pages 1-8.
[2] P. Toullec. “Relative Electrophilic Fluorinating Power as Assayed by Competitive Catalytic Halogenation Reactions.” ChemInform 56 1 (2005).
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| | 1-Fluoropyridinium tetrafluoroborate Preparation Products And Raw materials |
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