| Company Name: |
ChemeGen
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| Tel: |
18818260767 |
| Email: |
2625930290@qq.com |
| Products Intro: |
Product Name:13,14-dihydro Prostaglandin E1-d4
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:13,14-dihydro Prostaglandin E1-d4
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| Company Name: |
Santa Cruz Biotechnology Inc
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| Tel: |
021-60936350 |
| Email: |
scbt@scbt.com |
| Products Intro: |
Product Name:13,14-dihydro Prostaglandin E1-d4
|
| Company Name: |
Neobioscience Co., Ltd.
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| Tel: |
4006-800-892 |
| Email: |
info@neobioscience.com |
| Products Intro: |
Product Name:13,14-dihydro Prostaglandin E1-d4
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| | 13,14-DIHYDRO PROSTAGLANDIN E1-D4 Basic information |
| Product Name: | 13,14-DIHYDRO PROSTAGLANDIN E1-D4 | | Synonyms: | 13,14-DIHYDRO PROSTAGLANDIN E1-D4;9-OXO-11ALPHA,15S-DIHYDROXY-PROSTAN-1-OIC-3,3,4,4-D4 ACID;PGE0-D4 | | CAS: | | | MF: | C20H32D4O5 | | MW: | 360.52 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File |  |
| | 13,14-DIHYDRO PROSTAGLANDIN E1-D4 Chemical Properties |
| solubility | DMF: 50 mg/ml
DMSO: 50 mg/ml
Ethanol: 50 mg/mlPBS (pH 7.2): 1 mg/ml |
| | 13,14-DIHYDRO PROSTAGLANDIN E1-D4 Usage And Synthesis |
| Description | 13,14-dihydro Prostaglandin E1-d4 (13,14-dh PGE1-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 13,14-dh PGE1 by GC- or LC-mass spectrometry. 13,14-dh PGE1 is an inhibitor of ADP-induced platelet aggregation in human platelet-rich plasma and washed platelets with IC50 values of 31 and 21 nM, respectively.1 13,14-dh PGE1 is a slightly more potent inhibitor of ADP-induced human platelet aggregation than PGE1 which has an IC50 of 40 nM.2 Also, 13,14-dh PGE1 activates adenylate cyclase in NCB-20 hybrid cells with a Kact of 668 nM.3WARNING This product is not for human or veterinary use. | | References | [1] G. KOBZAR. Comparison of the inhibitory effect of E-prostaglandins in human and rabbit platelet-rich plasma and washed platelets[J]. Comparative Biochemistry and Physiology Part C: Pharmacology, Toxicology and Endocrinology, 1993, 106 2: Pages 489-494. DOI: 10.1016/0742-8413(93)90168-k
[2] I. JÄRVING. ANTIAGGREGATING POTENCY OF E-TYPE PROSTAGLANDINS IN HUMAN AND RABBIT PLATELETS[J]. Proceedings of the Estonian Academy of Sciences. Chemistry, 1991, 32 1. DOI: 10.3176/chem.1991.3.09
[3] I.A. BLAIR J. M C N HENSBY. PROSTACYCLIN-DEPENDENT ACTIVATION OF ADENYLATE CYCLASE IN A NEURONAL SOMATIC CELL HYBRID: PROSTANOID STRUCTURE-ACTIVITY RELATIONSHIPS[J]. British Journal of Pharmacology, 1980, 69 3: 519-525. DOI: 10.1111/j.1476-5381.1980.tb07043.x |
| | 13,14-DIHYDRO PROSTAGLANDIN E1-D4 Preparation Products And Raw materials |
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