| Company Name: |
Shanghai Boyle Chemical Co., Ltd.
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| Tel: |
021-50182298 021-50180596 |
| Email: |
sales@boylechem.com |
| Products Intro: |
Product Name:Estrone 3-O-SulfaMate
CAS:148672-09-7
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Tel: |
18210857532; 18210857532 |
| Email: |
jkinfo@jkchemical.com |
| Products Intro: |
Product Name:Estrone 3-O-SulfaMate
CAS:148672-09-7
Package:10Mg,1Mg
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| Company Name: |
3B Pharmachem (Wuhan) International Co.,Ltd.
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| Tel: |
821-50328103-801 18930552037 |
| Email: |
3bsc@sina.com |
| Products Intro: |
Product Name:ESTRONE 3-O-SULFAMATE
CAS:148672-09-7
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g
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| | ESTRONE 3-O-SULFAMATE Basic information |
| | ESTRONE 3-O-SULFAMATE Chemical Properties |
| Melting point | 195-197°C | | Boiling point | 530.9±60.0 °C(Predicted) | | density | 1.314±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | DMSO, Ethanol, Methanol | | pka | 8.86±0.70(Predicted) | | form | Solid | | color | Pale Beige | | Stability: | Hygroscopic | | InChIKey | RVKFQAJIXCZXQY-CBZIJGRNSA-N | | SMILES | C1(OS(N)(=O)=O)=CC2=C(C=C1)[C@]1([H])[C@]([H])([C@@]3([H])[C@@](CC1)(C)C(=O)CC3)CC2 |
| | ESTRONE 3-O-SULFAMATE Usage And Synthesis |
| Chemical Properties | White to Off-White Crystalline Solid | | Uses | A potent inhibitor of estrone sulfatase. Inhibits estrone sulfatase >99% at 0.1uM in intact MCF-7 cells, IC50=65pM. | | Purification Methods | Estrone 3-O-sulfamate [148672-09-7] M 349.5. Estrone 3-O-sulfamate is purified by silica gel flash chromatography to give a product with one spot on TLC. It is an active site-directed inhibitor of estrone sulfatase, i.e. a time-dependent enzyme inactivator. [Woo et al. J Med Chem 39 1349 1996, Purohit et al. Biochemistry 34 11508 1995.] |
| | ESTRONE 3-O-SULFAMATE Preparation Products And Raw materials |
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